700-85-6

Basic information

• Product Name: 1(3H)-ISOBENZOFURANONE, 5-FLUORO-
• Synonyms: 1(3H)-ISOBENZOFURANONE, 5-FLUORO-;5-FLUOROISOBENZOFURAN-1(3H)-ONE;5-Fluoro-1(3h)-isobenzofuranone
• CAS NO: 700-85-6
• Molecular Formula: C₈H₅FO₂
• Molecular Weight: 152.13
• Mol File: 700-85-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 118-119 °C
• Boiling Point: 322.686°C at 760 mmHg
• Flash Point: 144.107°C
• Appearance: /
• Density: 1.379g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1(3H)-ISOBENZOFURANONE, 5-FLUORO-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(3H)-ISOBENZOFURANONE, 5-FLUORO-(700-85-6)
• EPA Substance Registry System: 1(3H)-ISOBENZOFURANONE, 5-FLUORO-(700-85-6)

Safety Data

• Hazardous Substances Data: 700-85-6(Hazardous Substances Data)

Usage

General Description

1(3H)-Isobenzofuranone, 5-fluoro- is a chemical compound with the molecular formula C8H5FO2. It is also known as 5-fluoroisobenzofuranone and is a yellowish crystalline powder with a faint odor. 1(3H)-Isobenzofuranone, 5-fluoro- is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the production of dyes and pigments. Additionally, 1(3H)-Isobenzofuranone, 5-fluoro- has potential applications in the field of organic synthesis and medicinal chemistry. However, it is important to handle this compound with care as it may pose health risks and environmental hazards if not managed properly.

InChI:InChI=1/C8H5FO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3H,4H2

Upstream product

• 62558-08-1 4-fluoro-2-(hydroxymethyl)benzyl alcohol 
• 319-03-9 4-fluorophthalic anhydride 
• 202865-66-5 2-bromo-5-fluorobenzyl alcohol 

Downstream Products

• 114312-63-9 2-<(4-Fluorophenyl)oxymethyl>-4-fluorobenzoic acid 
• 105398-60-5 5-fluoro-3-oxo-1,3-dihydroisobenzofuran-1-carbonitrile 
• 93698-37-4 2-(4-chlorophenylthiomethyl)-4-fluorobenzoic acid 
• 93747-17-2 4-(4-chlorophenylthio)-2-(4-chlorophenylthiomethyl)benzoic acid 
• 139305-42-3 (E)-1-(3,8-Difluoro-6,11-dihydrodibenzoxepin-11-yl)-4-(3-phenyl-2-propenyl)piperazine dimaleate 
• 114312-29-7 (E)-1-(2,8-Difluoro-6,11-dihydrodibenzoxepin-11-yl)-4-(3-phenyl-2-propenyl)piperazine dimaleate 
• 114312-55-9 2,8-Difluoro-6,11-dihydrodibenzoxepin-11-one 

Relevant articles and documents

NOVEL COMPOUNDS USEFUL AS POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS

The present invention provides novel poly(ADP-ribose) polymerase (PARP) inhibitors, methods of preparing them, pharmaceutical compositions containing them and methods for the treatment, prevention and/or amelioration of PARP mediated diseases or disorders using them. In particular, the compounds described herein are useful for the treatment of carcinoma of the breast, ovarian cancer, carcinoma of the liver, carcinoma of the lung, small cell lung cancer, esophageal cancer, gall bladder cancer, pancreatic cancer and stomach cancer.

Dehydrogenative lactonization of diols in aqueous media catalyzed by a water-soluble iridium complex bearing a functional bipyridine ligand

A new catalytic system for the dehydrogenative lactonization of a variety of benzylic and aliphatic diols in aqueous media was developed. By using a water-soluble, dicationic iridium catalyst bearing 6,6′-dihydroxy-2, 2′-bipyridine as a functional ligand, highly atom economical and environmentally benign synthesis of various lactones was achieved in good to excellent yields. Recovery and reuse of the catalyst were also accomplished by a simple phase separation and the recovered catalyst maintained its high activity at least until the fifth run. Copyright