7065-27-2

Basic information

• Product Name: 4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine
• Synonyms: 4-[4-(Phenylsulfonyl)-2-(2-thienyl)-1,3-oxazol-5-yl]morpholine; morpholine, 4-[4-(phenylsulfonyl)-2-(2-thienyl)-5-oxazolyl]-
• CAS NO: 7065-27-2
• Molecular Formula: C₁₁H₁₀O
• Molecular Weight: 376.4499
• Mol File: 7065-27-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 615°C at 760 mmHg
• Flash Point: 325.8°C
• Density: 1.384g/cm³
• Vapor Pressure: 4.64E-15mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine(7065-27-2)
• EPA Substance Registry System: 4-[4-(phenylsulfonyl)-2-(thiophen-2-yl)-1,3-oxazol-5-yl]morpholine(7065-27-2)

Safety Data

• Hazardous Substances Data: 7065-27-2(Hazardous Substances Data)

Upstream product

• 68235-90-5 1-chloro-4-phenyl-2-methyl-3-butyn-2-ol 
• 78-95-5 chloroacetone 
• 536-74-3 phenylacetylene 
• 1463-04-3 (3-methylbut-3-en-1-ynyl)benzene 
• 1774-47-6 trimethylsulfoxonium iodide 
• 1817-57-8 4-phenyl-3-butyne-2-one 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 39517-83-4 4-methyl-2-phenylfuran 
• 68235-90-5 1-chloro-4-phenyl-2-methyl-3-butyn-2-ol 
• 17075-00-2 2-methyl-4-phenyl-3-butyn-1-ol 
• 100127-76-2 1-amino-2-methyl-4-phenyl-but-3-yn-2-ol 
• 39517-87-8 2-methyl-4-phenyl-but-3-yne-1,2-diol 
• 14300-29-9 3-Methyl-2-phenylthiophene 
• 106726-94-7 2-methyl-4-phenylbuta-2,3-dien-1-ol 
• 110410-96-3 3-benzylidene-2,5-dimethyl-2-hydroxymethyl-4-methoxycarbonyl-2,3-dihydrofuran 
• 34895-79-9 1-Cyano-2-methyl-4-phenyl-but-3-in-2-ol 
• 52385-67-8 2-methyl-4-phenylhexa-2,3-dien-1-ol 
• 52385-66-7 2-Methyl-4-phenyl-penta-2,3-dien-1-ol 
• 52385-68-9 2,5,5-Trimethyl-4-phenyl-hexa-2,3-dien-1-ol 
• 102747-59-1 1,2-bis-(4-methyl-2-phenyl-pyrrol-1-yl)-ethane 
• 101733-53-3 1-benzyl-4-methyl-2-phenyl-1H-pyrrole 

Relevant articles and documents

Palladium(II)-Catalyzed Regioselective syn-Hydroarylation of Disubstituted Alkynes Using a Removable Directing Group

A palladium(II)-catalyzed regioselective syn-hydroarylation reaction of homopropargyl amines has been developed, wherein selectivity is controlled by a cleavable bidentate directing group. Under the optimized reaction conditions, both dialkyl and alkylaryl alkyne substrates were found to undergo hydroarylation with high selectivity. The products of this reaction contain a 4,4-disubstituted homoallylic amine motif that is commonly seen in drug molecules and other bioactive compounds.

Efficient synthesis of substituted 3-iodofurans by electrophilic cyclization of propargylic oxirane derivatives

The electrophilic cyclization of various propargylic oxirane compounds and I2 offers an efficient and straightforward route to highly substituted iodofurans under mild reaction conditions. Further functionalization has demonstrated that the iod

Reactivity and Reactions of Aromatic Acetylenic Acids and Ketones

Some novel reactions of the acetylenic carboxylic acid, 4-oxo-6-phenylhexynoic acid with succinic anhydride are described.One of the products of the reaction is a butyrolactone derivative.Transformation of 4-phenylbut-3-yn-2-one results in the formation of α,β-acetylenic-α'-alkoxy epoxides which are of interest as anti-tumor compounds.