70709-65-8

Basic information

• Product Name: 3,3'-Dihydroxystilben
• Synonyms: 3,3'-Dihydroxystilben
• CAS NO: 70709-65-8
• Molecular Weight: 212.248
• Mol File: 70709-65-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 3,3'-Dihydroxystilben(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3'-Dihydroxystilben(70709-65-8)
• EPA Substance Registry System: 3,3'-Dihydroxystilben(70709-65-8)

Safety Data

• Hazardous Substances Data: 70709-65-8(Hazardous Substances Data)

Upstream product

• 74-85-1 ethene 
• 1415155-47-3 3-(non-8-enyl)phenol 
• 591-20-8 3-Bromophenol 
• 620-18-8 3-hydroxystyrene 
• 591-31-1 3-methoxy-benzaldehyde 
• 135203-60-0 diethyl <(3-benzyloxyphenyl)methyl>phosphonate 
• 1700-30-7 (3-(benzyloxy)phenyl)methanol 
• 1700-31-8 3-benzyloxybenzyl bromide 
• 1700-37-4 3-Benzyloxybenzaldehyde 
• 150258-72-3 (E)-1-<3-(benzyloxy)phenyl>-2-<3-(benzyloxy)phenyl>ethene 
• 6325-63-9 (E)-3,3'-dimethoxystilbene 
• 621-37-4 m-hydroxyphenylacetic acid 
• 70709-70-5 (E)-2,3-Bis-(3-hydroxy-phenyl)-acrylic acid 
• 100-83-4 meta-hydroxybenzaldehyde 

Downstream Products

• 70709-67-0 3,3'-(ethane-1,2-diyl)diphenol 
• 1173144-36-9 C₂₂H₂₄O₆ 
• 1229393-74-1 E-3,3'-(1,2-ethenediyl)bis[2-[(dimethylamino)methyl]phenol] 

Relevant articles and documents

A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride via a Membrane-Associated Mechanism

Targeting Streptococcus mutans is the primary focus in reducing dental caries, one of the most common maladies in the world. Previously, our groups discovered a potent bactericidal biaryl compound that was inspired by the natural product honokiol. Herein, a structure activity relationship (SAR) study to ascertain structural motifs key to inhibition is outlined. Furthermore, mechanism studies show that bacterial membrane disruption is central to the bacterial growth inhibition. During this process, it was discovered that analog C2 demonstrated a 4-fold better therapeutic index compared to the commercially available antimicrobial cetylpyridinium chloride (CPC) making it a viable alternative for oral care.

Inhibitory effect of cytotoxic stilbenes related to resveratrol on the expression of the VEGF, hTERT and c-Myc genes

A group of thirty-nine stilbene derivatives, prepared by means of Heck coupling reactions, has been investigated for their cytotoxicity, as well as for their ability to inhibit the production of the vascular endothelial growth factor (VEGF) and the activation of telomerase. The ability of these compounds to inhibit proliferation of two tumoral cell lines (HT-29 and MCF-7) and one non tumoral cell line (HEK-293) was first determined. Subsequently, we determined the capacity of the compounds to inhibit the secretion of VEGF in the aforementioned cell lines and to downregulate the expression of the VEGF, hTERT and c-Myc genes, the two latter involved in the control of the activation of telomerase. One of the synthetic stilbenes, (E)-4-(4-methoxystyryl)aniline, showed strong cytotoxicity and proved able to cause a marked decrease both in the secretion of VEGF and in the expression of the hTERT and c-Myc genes, in all cases at concentrations in the low nanomolar range.

Ionic-liquid-influenced expeditious and stereoselective synthesis of olefins

1-Butyl-3-methylimidazolium chloroaluminate, [bmim]Cl·.AlCl3 (molar fraction, N=0.67), ionic liquid has been used in combination with metallic Zn for the reductive coupling of carbonyl compounds to synthesize symmetrical olefins, with the Z-isomer formed predominantly. The ionic liquid played a dual role of Lewis acid catalyst and solvent. Copyright Taylor & Francis Group, LLC.