70709-67-0

Basic information

• Product Name: Phenol, 3,3'-(1,2-ethanediyl)bis-
• CAS NO: 70709-67-0
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Mol File: 70709-67-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 3,3'-(1,2-ethanediyl)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3,3'-(1,2-ethanediyl)bis-(70709-67-0)
• EPA Substance Registry System: Phenol, 3,3'-(1,2-ethanediyl)bis-(70709-67-0)

Safety Data

• Hazardous Substances Data: 70709-67-0(Hazardous Substances Data)

Upstream product

• 36707-27-4 1,2-bis(3-methoxyphenyl)ethane 
• 6325-63-9 1,2-bis(3-methoxyphenyl)ethylene 
• 70709-65-8 (E)-1-(3-hydroxyphenyl)-2-(3-hydroxyphenyl)ethene 
• 100-83-4 meta-hydroxybenzaldehyde 
• 70709-70-5 (E)-2,3-Bis-(3-hydroxy-phenyl)-acrylic acid 
• 621-37-4 m-hydroxyphenylacetic acid 
• 824-98-6 m-methoxybenzyl chloride 
• 40101-17-5 3,3'-dimethoxybenzil 
• 6971-51-3 3-methoxybenzyl alcohol 
• 70709-65-8 3,3'-Dihydroxystilben 
• 108-39-4 3-methyl-phenol 
• 75-26-3 isopropyl bromide 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 507-19-7 t-butyl bromide 

Downstream Products

• 1191419-08-5 1,2-bis(3-butoxyphenyl)ethane 

Relevant articles and documents

A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride via a Membrane-Associated Mechanism

Targeting Streptococcus mutans is the primary focus in reducing dental caries, one of the most common maladies in the world. Previously, our groups discovered a potent bactericidal biaryl compound that was inspired by the natural product honokiol. Herein, a structure activity relationship (SAR) study to ascertain structural motifs key to inhibition is outlined. Furthermore, mechanism studies show that bacterial membrane disruption is central to the bacterial growth inhibition. During this process, it was discovered that analog C2 demonstrated a 4-fold better therapeutic index compared to the commercially available antimicrobial cetylpyridinium chloride (CPC) making it a viable alternative for oral care.

Synthesis of potential bisphenol A substitutes by isomerising metathesis of renewable raw materials

Isomerising metathesis is introduced as a sustainable method to produce dihydroxystilbene derivatives from eugenol, a clove oil ingredient, and cardanol from cashew nut shell liquid. Hydrogenation of the dihydroxystilbenes provided their di(hydroxyphenyl)ethane analogues. Initial studies to convert these monomers into polycarbonates and thiol-ene polymers support their potential to replace the petrol-derived bisphenol A (BPA). The estrogenic activity of the monomers derived from cardanol was found to be in the same range as that of BPA, a known endocrine disruptor. In contrast, eugenol-derived materials were found to be non-estrogenic, opening up new perspectives for bio-based food packaging materials.

Selective labeling of living cells by a photo-triggered click reaction

Phototriggering of the metal-free azide to acetylene cycloaddition reaction was achieved by masking the triple bond of dibenzocyclooctynes as cyclopropenone. Such masked cyclooctynes do not react with azides in the dark. Irradiation of cyclopropenones res