72120-54-8

Basic information

• Product Name: Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester
• Synonyms: 1-(Benzyloxycarbonyl)hexahydropyridazine-3-carboxylic acid;Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester;1-Cbz-tetrahydropyridazine-3-carboxylic acid
• CAS NO: 72120-54-8
• Molecular Formula: C₁₃H₁₆N₂O₄
• Molecular Weight: 264.28
• Mol File: 72120-54-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 440.176 °C at 760 mmHg
• Flash Point: 220.011 °C
• Appearance: /
• Density: 1.294
• Storage Temp.: 2-8°C
• PKA: 2.07±0.20(Predicted)
• CAS DataBase Reference: Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester(72120-54-8)
• EPA Substance Registry System: Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester(72120-54-8)

Safety Data

• Hazardous Substances Data: 72120-54-8(Hazardous Substances Data)

Usage

General Description

Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester is a complex chemical compound. Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester belongs to the pyridazines class of chemicals, which is primarily characterized by a six-membered ring with two nitrogen atoms. The other component in this compound is a carboxylic acid ester. Carboxylic acids are organic compounds that contain a carboxyl group, and in this case, it is attached to an ester, an organic compound made by replacing the hydrogen of an acid by an alkyl or other organic group. The final part of this compound, phenylmethyl, refers to the introduction of a phenyl group. The combination of these various components gives Tetrahydro-1,3(2H)-pyridazinedicarboxylic acid 1-(phenylmethyl) ester its unique chemical properties.

Upstream product

• 1219380-72-9 N,N'-di-tert-butoxycarbonylpiperazic acid 
• 626-99-3 1,3-butadiene-1-carboxylic acid 
• 501-53-1 benzyl chloroformate 
• 62221-99-2 hexahydro-1,2-dioxo-2-phenyl-s-triazolo<1,2-a>pyridazine-5-carboxylic acid 

Downstream Products

• 81383-51-9 1-benzyl 3-tert.butyl 2-(2-ethoxycarbonyl-2-methylacetyl)hexahydropyridazine-1,3-dicarboxylate 
• 81383-49-5 t-butyl 1-benzyloxycarbonylhexahydropyridazine-3-carboxylate 

Relevant articles and documents

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Process for preparing hexahydropyridazine-3-carboxylic acid derivatives

According to the process of the invention, the hexahydropyridazine-3-carboxylic acid derivatives are prepared by reacting a compound of formula (II) with a compound of formula (III) in the presence of a base with a pK of greater than or equal to 8.5, in a ketone organic solvent, to obtain an intermediate compound that is not isolated and that is treated with a basic aqueous medium. By means of this process, the derivatives are obtained more quickly and more economically.