72228-97-8

Basic information

• Product Name: Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, methyl ester, (1R,2R)-rel-
• CAS NO: 72228-97-8
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol File: 72228-97-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, methyl ester, (1R,2R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, methyl ester, (1R,2R)-rel-(72228-97-8)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 2-(4-methylphenyl)-, methyl ester, (1R,2R)-rel-(72228-97-8)

Safety Data

• Hazardous Substances Data: 72228-97-8(Hazardous Substances Data)

Upstream product

• 20754-20-5 3-p-tolyl-acrylic acid methyl ester 
• 1774-47-6 trimethylsulfoxonium iodide 
• 1866-39-3 trans-p-methylcinnamic acid 
• 186581-53-3 diazomethane 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 6832-16-2 methyl diazoacetate 

Downstream Products

• 114095-61-3 (trans-2-(4-methylphenyl)cyclopropyl)methanol 
• 132145-62-1 trans-2-(p-tolyl)cyclopropane-1-carbaldehyde 
• 220349-91-7 (1R,2S)-2-p-Tolyl-cyclopropylamine 
• 16633-44-6 (±)-trans-2-p-tolylcyclopropanecarboxylic acid 

Relevant articles and documents

Enantioselective Copper-Catalyzed 1,5-Cyanotrifluoromethylation of Vinylcyclopropanes

A copper-catalyzed enantioselective 1,5-cyanotrifluoromethylation of vinylcyclopropanes has been developed using a radical relay strategy. This asymmetric reaction has demonstrated high enantioselective control, broad substrate scope, and mild conditions. Initiated by the in situ generated CF3 radical from Togni's reagent, this method offers a new solution for remote enantioselective bifunctionalization of alkenes and thus provides a straightforward way for the synthesis of chiral CF3-containing internal alkenylnitriles.

Transition-Metal-Catalyzed Reactions of Diazo Compounds. 1. Cyclopropanation of Double Bonds

Rhodium(II) and palladium(II) carboxylates are efficient catalysts for the cyclopropanation of olefins by diazo esters.Intramolecular competitions within diolefins and intermolecular competitions between pairs of monoolefins showed quite different cyclopr