72545-41-6

Basic information

• Product Name: 2',4',5,5',7-pentamethoxyisoflavone
• Synonyms: 2',4',5,5',7-pentamethoxyisoflavone
• CAS NO: 72545-41-6
• Molecular Weight: 372.375
• Mol File: 72545-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2',4',5,5',7-pentamethoxyisoflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 2',4',5,5',7-pentamethoxyisoflavone(72545-41-6)
• EPA Substance Registry System: 2',4',5,5',7-pentamethoxyisoflavone(72545-41-6)

Safety Data

• Hazardous Substances Data: 72545-41-6(Hazardous Substances Data)

Upstream product

• 6468-53-7 2-hydroxy-2',4,4',5',6-pentamethoxybenzoin 
• 4463-16-5 2,4,5-trimethoxyphenylacetic acid 
• 38444-50-7 2,4,5-trimethoxybenzeneacetonitrile 
• 18113-21-8 chloroglucinol dimethyl ether 
• 75340-02-2 5,7-dihydroxy-3-(2,4,5-trimethoxyphenyl)chromen-4-one 
• 74-88-4 methyl iodide 

Relevant articles and documents

Synthesis of 5,7-Dihydroxy-2',4',5'-trimethoxyisoflavone and Its 7-Methyl Ether (Robustigenin)

The treatment of 2,4,6-trihydroxy-2',4',5'-trimethoxydeoxybenzoin with benzyl chloride gave a dibenzyl ether.The condensation of the ether with ethyl formate, followed by the debenzylation of the resulting isoflavone, afforded 5,7-dihydroxy-2',4',5'-trimethoxyisoflavone, which was then converted into a pentamethoxyisoflavone.The partial demethylation of the pentamethoxyisoflavone gave 5-hydroxy-2',4',5',7'-tetramethoxyisoflavone, which was identical with natural robustigenin.