727418-77-1Relevant articles and documents
A new strategy for 2-substituted indolylalkylamines: Synthesis of 2-aryldihomotryptamines
Nenajdenko, Valentine G,Zakurdaev, Eugene P,Balenkova, Elizabeth S
, p. 8449 - 8451 (2002)
Substituted homologues of tryptamines were synthesized in one step in high yields under mild conditions. The key intermediates are arylhydrazones of 6-aminohexanones, which undergo Fischer rearrangement readily in glacial acetic acid. An easy and ready for scale-up procedure is developed and formerly unknown 2-substituted dihomotryptamines are obtained.
