73193-05-2

Basic information

• Product Name: Cyclohexanone, 2-chloro-6-methyl-
• Synonyms: 2-chloro-6-methylcyclohexanone;cyclohexanone,2-chloro-6-methyl;2-Chlor-6-methyl-cyclohexanon
• CAS NO: 73193-05-2
• Molecular Formula: C7H11ClO
• Molecular Weight: 146.617
• Mol File: 73193-05-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Cyclohexanone, 2-chloro-6-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanone, 2-chloro-6-methyl-(73193-05-2)
• EPA Substance Registry System: Cyclohexanone, 2-chloro-6-methyl-(73193-05-2)

Safety Data

• Hazardous Substances Data: 73193-05-2(Hazardous Substances Data)

Upstream product

• 63031-68-5 2-(trimethylsilyl)-3-methylcyclohexene 
• 70871-39-5 6-Methyl-1-methylsulfanyl-cyclohexene 
• 583-60-8 2-Methylcyclohexanone 
• 128-09-6 N-chloro-succinimide 
• 98-59-9 p-toluenesulfonyl chloride 
• 19980-33-7 6-methyl-1-trimethylsiloxycyclohex-1-ene 

Downstream Products

• 131591-93-0 methyl-(3-methyl-2-oxo-cyclohexyl)-malonic acid diethyl ester 
• 128126-32-9 1,2-di(ethylthio)-3-methyl-1-cyclohexene 
• 84459-46-1 1-Methyl-6-phenylcyclohexan-1-one 
• 99181-55-2 2-(3-methyl-2-oxocyclohexyl)propionic acid 
• 128101-81-5 1,2-di(butylthio)-3-methyl-1-cyclohexene 
• 128126-33-0 1,2-di(propylthio)-3-methyl-1-cyclohexene 

Relevant articles and documents

Efficient α-chlorination of carbonyl containing compounds under basic conditions using methyl chlorosulfate

An efficient method for the α-chlorination of ketones under basic conditions is described using methyl chlorosulfate. Its applicability for the chlorination of other functional groups has also been studied and it is equally useful for the synthesis of α-chloroesters and amides. Methyl chlorosulfate is described for the first time as a positive chlorine source. Some aldol reactions which occur during the chlorination of some substrates are also reported.

Rapid and catalyst-free α-halogenation of ketones using N-halosuccinamides in DMSO

α-Halogenation of various carbonyl compounds such as β-keto-esters, cyclic ketones, and lactams with N-halosuccinamides (NBS, NCS, NIS) in the presence of DMSO proceeded very smoothly to give the corresponding α-monohalogenated products in good to excellent yields with high selectivity under catalyst-free conditions. Copyright Taylor & Francis Group, LLC.

Amberlyst-15-promoted efficient 2-halogenation of 1,3-keto-esters and cyclic ketones using N-halosuccinimides

A simple and rapid process has been developed for the α- monohalogenation of 1,3-keto-esters with N-halosuccinimides catalyzed by Amberlyst-15 at room temperature to produce the corresponding 2-halo 1,3-keto-esters in high yields. This protocol also extended to α-halogenation of cyclic ketones.