73318-30-6

Basic information

• Product Name: 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE
• Synonyms: 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE;3-(2-methylphenyl)isochromen-1-one
• CAS NO: 73318-30-6
• Molecular Formula: C₁₆H₁₂O₂
• Molecular Weight: 236.27
• Mol File: 73318-30-6.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 395.4°C at 760 mmHg
• Flash Point: 166.5°C
• Appearance: /
• Density: 1.208g/cm³
• Vapor Pressure: 1.84E-06mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE(73318-30-6)
• EPA Substance Registry System: 3-(2-TOLYL)-1H-2-BENZOPYRAN-1-ONE(73318-30-6)

Safety Data

• Hazardous Substances Data: 73318-30-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H12O2/c1-11-6-2-4-8-13(11)15-10-12-7-3-5-9-14(12)16(17)18-15/h2-10H,1H3

Upstream product

• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 78752-29-1 o-<(trimethylsilyl)methyl>benzoyl chloride 
• 3469-06-5 benzocyclobutenone 
• 2728-04-3 N,N-diethyl-ortho-toluamide 
• 119-36-8 methyl salicylate 
• 118-90-1 ortho-methylbenzoic acid 
• 89-51-0 Homophthalic acid 
• 933-88-0 ortho-toluoyl chloride 
• 7127-19-7 2-phenyl-1,3-oxazoline 
• 88-67-5 2-Iodobenzoic acid 
• 766-47-2 1-ethynyl-2-methylbenzene 
• 98-88-4 benzoyl chloride 
• 2446-51-7 N-methoxybenzamide 
• 72591-20-9 1-bromo-2-(ortho-methylphenyl)ethyne 

Downstream Products

• 54463-74-0 3-o-tolyl-isoquinolin-1-ol 

Relevant articles and documents

Sulfoxonium Ylides as Carbene Precursors: Rhodium(III)-Catalyzed Sequential C?H Functionalization, Selective Enol Oxygen-Atom Nucleophilic Addition, and Hydrolysis

Herein, we report a protocol for Rh(III)-catalyzed annulation reactions between oxazolines and sulfoxonium ylides via a sequence involving C?H activation, selective enol oxygen-atom nucleophilic addition, and hydrolysis. This practical, operationally simple protocol has a wide substrate range, excellent regioselectivity, and moderate to good yields.

Rhodium(III)-catalyzed chemodivergent annulations between: N-methoxybenzamides and sulfoxonium ylides via C-H activation

Chemodivergent and redox-neutral annulations between N-methoxybenzamides and sulfoxonium ylides have been realized via Rh(iii)-catalyzed C-H activation. The sulfoxonium ylide acts as a carbene precursor, and coupling occurs under acid-controlled condition

Copper-catalyzed annulation of 2-bromobenzoic esters with terminal alkynes towards 3-substituted isocoumarins

An efficient method for the synthesis of 3-substituted isocoumarins that are an important class of biologically active scaffolds via annulation of 2-bromobenzoic esters with terminal alkynes by copper catalyzed is described. The advantages of this method include mild reaction conditions, high yield and regioselectivity, and wide tolerance toward functional groups.