7370-14-1

Basic information

• Product Name: 1-Cyclohexene-1-carbonitrile, 4-(1,1-dimethylethyl)-
• CAS NO: 7370-14-1
• Molecular Formula: C11H17N
• Molecular Weight: 163.263
• Mol File: 7370-14-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexene-1-carbonitrile, 4-(1,1-dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexene-1-carbonitrile, 4-(1,1-dimethylethyl)-(7370-14-1)
• EPA Substance Registry System: 1-Cyclohexene-1-carbonitrile, 4-(1,1-dimethylethyl)-(7370-14-1)

Safety Data

• Hazardous Substances Data: 7370-14-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Molecular weight

179.27 g/mol

Usage

Production of pharmaceuticals, agrochemicals, and other organic compounds; intermediate in the synthesis of various chemical compounds

Structure

Cyclohexene ring with a carbonitrile functional group and a tert-butyl substituent

Health hazards

Potential health hazards, should be handled with care in a controlled environment

Upstream product

• 941-44-6 4-tert-butyl-1-hydroxy-cyclohexanecarbonitrile 
• 5807-02-3 4-morpholinoacetonitrile 
• 31865-37-9 cis/trans-4-tert-Butylcyclohexancarbonitril 
• 110890-79-4 4-tert-Butyl-1-nitromethylcyclohexene 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 16499-32-4 <1-Cyan-4-tert-butyl-cyclohexyl>-dimethylamin 
• 119061-98-2 1-(tributylstannyl)-4-tert-butylcyclohexene 
• 63031-67-4 4-(1,1-dimethylethyl)cyclohexen-1-yltrimethylsilane 
• 10442-39-4 tetra-n-butylammonium cyanide 
• 13682-73-0 Potassium dicyanocuprate 
• 129548-52-3 4-tert-Butyl-cyclohex-1-enecarbaldehyde oxime 

Downstream Products

• 96759-30-7 N-methyl-4-tert-butyl-1-cyclohexenecarboxamide 
• 1352304-58-5 2-(4-tert-butylcyclohex-1-enyl)-5,5-dimethyl-1,3,2-dioxaborinane 
• 54923-65-8 (4-tert-Butylcyclohex-1-enyl)methanol 
• 54923-67-0 Carbaethoxy-2(t-butyl-4-cyclohexen-1-yl)-3-aethylpropionat 
• 54923-68-1 Carboxy-2(t-butyl-4-cyclohexen-1-yl)-3-propionsaeure 
• 54923-66-9 Brommethyl-1-t-butyl-4-cyclohexen 
• 22642-99-5 1-((1S,2S,4R)-4-tert-Butyl-2-methyl-cyclohexyl)-ethanone 
• 22173-19-9 4-tert-butyl-1-cyclohexene-1-carboxylic acid methyl ester 
• 41601-72-3 1-isopropenyl-4-t-butylcyclohexene 
• 41601-70-1 2-(4-tert-Butyl-cyclohex-1-enyl)-propan-2-ol 
• 127081-19-0 (1R,2R)-5-tert-Butyl-3'-oxo-bicyclohexyl-1'-ene-2-carbonitrile 
• 127081-15-6 (1R,2R,4R)-2-Benzoyl-4-tert-butyl-cyclohexanecarbonitrile 
• 63031-67-4 4-(1,1-dimethylethyl)cyclohexen-1-yltrimethylsilane 
• 130648-83-8 2-diphenylphosphino-4-t-butyl-1-cyanocyclohexane 

Relevant articles and documents

Cyanation of Phenol Derivatives with Aminoacetonitriles by Nickel Catalysis

Generation of useful arylnitrile structures from simple aromatic feedstock chemicals represents a fundamentally important reaction in chemical synthesis. The first nickel-catalyzed cyanation of phenol derivatives with metal-free cyanating agents, aminoacetonitriles, is described. A nickel-based catalytic system consisting of a unique diphosphine ligand such as dcype or dcypt enables the cyanation of versatile phenol derivatives such as aryl carbamates and aryl pivalates. The use of aminoacetonitriles as a cyanating agent leads to an environmentally and easy-to-use method for arylnitrile synthesis.

Michael addition of cyanide to cyclohex-1-enyliodonium salts

Reaction of 4-substituted cyclohex-1-enyliodonium salt with cyanide in chloroform produces three isomeric cyanocyclohexenes, ipso and two cine products. Deuterium labeling experiments showed that the allylic cine product is formed via the Michael addition of cyanide, followed by elimination of the iodonio group and a 1,2-H shift.

One-pot Conversion of Allylic Nitro Compounds Into Nitriles with Carbon Disulphide under Phase-transfer Catalysis Conditions

An one-pot synthesis of allylic nitriles 3 from the corresponding nitro derivatives 1 is described.In the first step the substrates 1 are reduced to the oximes 2 by carbon disulphide in the presence of wet potassium carbonate, in solid-liquid PTC conditions.In the second, the formed oximes 2 are dehydrated by adding more CS2 and 15percent aqueous NaOH.