737828-53-4

Basic information

• Product Name: (2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-[(4-methyl-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
• Synonyms: (2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-[(4-methyl-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester
• CAS NO: 737828-53-4
• Molecular Weight: 605.177
• Mol File: 737828-53-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-[(4-methyl-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-[(4-methyl-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester(737828-53-4)
• EPA Substance Registry System: (2-{4-[(4-chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-2-oxo-ethyl)-[(4-methyl-benzylcarbamoyl)-methyl]-carbamic acid tert-butyl ester(737828-53-4)

Safety Data

• Hazardous Substances Data: 737828-53-4(Hazardous Substances Data)

Upstream product

• 303-26-4 N-(4-chlorobenzhydryl)piperazine 
• 191281-21-7 N-((tert-butyloxy)carbonyl)-N'-(4-methylbenzyl) iminodiacetic acid monoamide 
• 56074-21-6 N-((tert-butyloxy)carbonyl)iminodiacetic acid anhydride 
• 56074-20-5 N-((tert-butyloxy)carbonyl)iminodiacetic acid 

Relevant articles and documents

Synthesis and evaluation of (4-chlorobenzhydryl) piperazine amides as sodium channel Nav1.7 inhibitors

Blockage of voltage-gated sodium channels is used to treat neuropathic pain which is chronic and can become debilitating. Sodium channels Nav1.7-1.9 are especially attractive targets for drug discovery because of the broad therapeutic potential of their m