742-43-8Relevant articles and documents
Ln(OTf)3- or Cu(OTf)2-catalyzed Mannich-type reactions of aldehydes, amines, and silyl enolates in micellar systems. Facile synthesis of β-amino ketones and esters in water
Kobayashi, Shu,Busujima, Tsuyoshi,Nagayama, Satoshi
, p. 545 - 546 (1999)
In the presence of a catalytic amount of Ln(OTf)3 or Cu(OTf)2, three- component Mannich-type reactions of aldehydes, amines, and silyl enolates proceeded smoothly in micellar systems to afford the corresponding β-amino ketones or est
Synthesis of β-Amino Ketones using graphene oxide: a benign carbonaceous acid catalyst for Mannich reaction
Saravana Ganesan, Nagappan,Suresh, Palaniswamy
, p. 1197 - 1210 (2021/01/07)
Abstract: Simple and easily preparable graphene oxide (GO) is used as a straightforward carbocatalyst for the synthesis of β-amino ketones via a 3-component Mannich reaction under mild condition. The native GO is acting as a carbonaceous solid Br?nsted acid catalyst without any special functionalization, yielding a spectrum of β-amino ketones under metal-free conditions. The present catalytic method offers a benign and simple procedure without any hazardous workup, and chromatographic purification resulted in an excellent yield of β-amino ketones. The catalyst has shown good sustainability up to 6 consecutive catalytic cycles without any significant loss in its activity. The stability of the recovered catalyst is proved by analytical techniques such as FT-IR, PXRD, SEM, and TEM. This mild solid-acid catalyst offers an alternative and sustainable approach to get synthetically essential β-amino ketones under greener conditions. Graphical abstract: [Figure not available: see fulltext.].
Tuning Microenvironment of Quaternary Ammonium Salt and Tertiary Amine Bifunctionalized Polyacrylonitrile Fiber for Cooperatively Catalyzed Aza-Michael Addition
Yuan, Xueyu,Du, Huimin,Zhao, Jingyan,Chima, Anyaegbu Ejike,Ma, Ning,Tao, Minli,Zhang, Wenqin
, p. 832 - 843 (2020/08/10)
A series of novel polyacrylonitrile fiber catalysts modified with different ratio of quaternary ammonium salt (QA) to tertiary amine (TA) were screened for heterogeneously catalyzed aza-Michael addition in water. The best catalyst was found to be PAN
