75305-81-6

Basic information

• Product Name: Propanoic acid, 2-methyl-, 4-acetylphenyl ester
• CAS NO: 75305-81-6
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 75305-81-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-methyl-, 4-acetylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-methyl-, 4-acetylphenyl ester(75305-81-6)
• EPA Substance Registry System: Propanoic acid, 2-methyl-, 4-acetylphenyl ester(75305-81-6)

Safety Data

• Hazardous Substances Data: 75305-81-6(Hazardous Substances Data)

Upstream product

• 97-72-3 2-Methylpropionic anhydride 
• 99-93-4 4-Hydroxyacetophenone 
• 79-30-1 isobutyryl chloride 

Downstream Products

• 476360-70-0 isobutyric acid 4-[3-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-8-oxo-5,8-dihydro-3H-1,3,4,5,7a-pentaaza-s-indacen-6-yl]-phenyl ester 
• 476360-62-0 isobutyric acid 4-[3-(2-hydroxy-ethoxymethyl)-8-oxo-5,8-dihydro-3H-1,3,4,5,7a-pentaaza-s-indacen-6-yl]-phenyl ester 
• 476360-57-3 4-isobutyryloxyphenacyl bromide 

Relevant articles and documents

Synthesis and biological activity of strongly fluorescent tricyclic analogues of acyclovir and ganciclovir

In search of strongly fluorescent tricyclic analogues of acyclovir (ACV, 1) and ganciclovir (GCV, 2), derivatives of the 3,9-dihydro-9-oxo-5H-imidazo[1,2-α]purine system, several 6-[4- (acyloxy)-phenyl], 6-[4-(acylamino)phenyl], and 6-[4-(phenoxycarbonyloxy)phenyl]-substituted TACV and TGCV analogues were synthesized and evaluated for their activity against herpes simplex virus types 1 and 2 in cell culture. All TACV and TGCV analogues showed strong fluorescence (quantum yield of 30-65% vs 2-aminopurine 100%). The 6-[4-(phenoxycarbonyloxy)phenyl]-substituted compounds 11 and 19 displayed the best combination of the fluorescence and antiviral potency.