75371-78-7

Basic information

• Product Name: 4-Pentenoic acid, 3-methyl-, (R)-
• Synonyms: (R)-3-methylpentenoic acid;(R)-3-Methyl-pent-4-enoic acid;(R)-3-methyl-4-pentenoic acid
• CAS NO: 75371-78-7
• Molecular Formula: C6H10O2
• Molecular Weight: 114.144
• Mol File: 75371-78-7.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 107 °C (3 mmHg)
• Density: 0.969±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Pentenoic acid, 3-methyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pentenoic acid, 3-methyl-, (R)-(75371-78-7)
• EPA Substance Registry System: 4-Pentenoic acid, 3-methyl-, (R)-(75371-78-7)

Safety Data

• Hazardous Substances Data: 75371-78-7(Hazardous Substances Data)

Upstream product

• 107-80-2 1,3-dibromobutane 
• 105-53-3 diethyl malonate 
• 250687-61-7 methyl 2,3-di-O-benzyl-6-deoxy-4-O-[(R)-3-methyl-4-pentenoyl]-α-D-glucopyranoside 
• 96864-23-2 (R)-3-Methyl-pent-4-enoic acid (1S,2R,4R)-1-[(dicyclohexylsulfamoyl)-methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 1445-45-0 Trimethyl orthoacetate 
• 6117-91-5 (E/Z)-2-buten-1-ol 
• 154260-99-8 (E)-2-Dipropylamino-3-(1-methyl-allyl)-but-2-enedioic acid dimethyl ester 
• 154261-03-7 (E)-2-(1-Methyl-allyl)-3-pyrrolidin-1-yl-but-2-enedioic acid dimethyl ester 
• 20459-97-6 3-Methyl-4-pentensaeure-methylester 
• 78-39-7 Triethyl orthoacetate 
• 504-61-0 (E)-but-2-enol 
• 7379-74-0 β-vinyl-β-propiolactone 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 75826-34-5 dihydro-4-methyl-5-<(phenylseleno)methyl>-2(3H)-furanone 
• 374822-48-7 C₆H₁₃NO 
• 176966-87-3 tert-butyl (3S,4R)-3-hydroxy-4-methyl-piperidine-1-carboxylate 
• 850833-79-3 3-methyl-pent-4-enoic acid (3-{[(3-hexanoylamino-phenylcarbamoyl)-methyl]-carbamoyl}-4-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-phenylcarbamoyl)-methyl ester 
• 75826-34-5 (+/-)-3α-methyl-4β(selenophenylmethyl)-γ-butyrolactone 
• 75826-34-5 cis-5-phenylseleno-3-methyl-4-pentanolide 
• 121190-27-0 N-phenyl-3-methyl-4-pentenamide 
• 1777-33-9 3-methyl-4-pentenal 

Relevant articles and documents

Synthesis of 5-[(Pentafluorosulfanyl)methyl]-γ-butyrolactones via a Silver-Promoted Intramolecular Cyclization Reaction

The synthesis of 5-[(pentafluorosulfanyl)methyl]-γ-butyrolactones bearing different substituents at position 3 or 4 is reported. A silver-promoted intramolecular cyclization of substituted 4-chloro-5-(pentafluorosulfanyl)pentanoic acids allows the preparation of the substituted SF5-containing γ-butyrolactones in up to 96 % yield.

Pd(II)-catalyzed allylic C-H amination for the preparation of 1,2- and 1,3-cyclic ureas

A general synthesis of 1,2- and 1,3-cyclic ureas is accomplished by intramolecular allylic C-H amination employing Pd(TFA)2/bis-sulfoxide as a catalyst. By careful modification of substrates and catalyst, a variety of 1,2-cyclic ureas are accessible from not previously employed terminal olefins substituted in allylic or vinylic positions. Furthermore, MS4A is found to be an effective additive for the synthesis of 1,3-cyclic ureas in good yields and excellent diastereoselectivities.

Acyloxylactonisations mediated by lead tetracarboxylates

The reaction of lead(IV) tetracarboxylates with carboxylic acids containing unsaturated side chains has been found to give acyloxy lactone products in a diastereoselective process; the reaction can be extended to lead(IV) tetrazolates to give the analogous outcome. Mechanistic implications of these results are discussed.