7540-51-4Relevant articles and documents
Nickel Hydride Catalyzed Cleavage of Allyl Ethers Induced by Isomerization
Kathe, Prasad M.,Berkefeld, Andreas,Fleischer, Ivana
supporting information, p. 1629 - 1632 (2021/02/09)
This report discloses the deallylation of O - and N -allyl functional groups by using a combination of a Ni-H precatalyst and excess Bronsted acid. Key steps are the isomerization of the O - or N -allyl group through Ni-catalyzed double-bond migration followed by Bronsted acid induced O/N-C bond hydrolysis. A variety of functional groups are tolerated in this protocol, highlighting its synthetic value.
Asymmetric synthesis of γ-chiral borylalkanes: Via sequential reduction/hydroboration using a single copper catalyst
Han, Jung Tae,Lee, Jin Yong,Yun, Jaesook
, p. 8961 - 8965 (2020/11/23)
The synthesis of γ-chiral borylalkanes through copper-catalyzed enantioselective SN2′-reduction of γ,γ-disubstituted allylic substrates and subsequent hydroboration was reported. A copper-DTBM-Segphos catalyst produced a range of γ-chiral alkylboronates from easily accessible allylic acetate or benzoate with high enantioselectivities up to 99% ee. Furthermore, selective organic transformations of the resulting γ-chiral alkylboronates generated the corresponding γ-chiral alcohol, arene and amine compounds.
Method for synthesizing levorotatory citronellol by asymmetric hydrosilation of citral
-
Paragraph 0010; 0049-0065, (2020/04/17)
The invention provides a method for synthesizing levorotatory citronellol from citral through asymmetric hydrosilation. The method comprises following steps: under the catalytic action of a chiral ruthenium complex, monohydrosilane is used as a hydrosilylation reagent, a Lewis acid is used as an auxiliary agent, and citral is subjected to asymmetric hydrosilylation to obtain levorotatory citronellol. According to the method, the ruthenium complex which is relatively low in price is used as the catalyst, meanwhile, the use amount of the ruthenium complex is effectively reduced, the maximum molar ratio of the chiral ruthenium complex to citral can reach 1: 30000, and the cost of the catalyst is remarkably reduced.