76-00-6

Basic information

• Product Name: 1,1,1-TRICHLORO-2-PROPANOL
• Synonyms: 1,1,1-trichloro-2-propano;1,1,1-Trichloroisopropyl alcohol;1,1,1-trichloroisopropylalcohol;2,2,2-Trichloro-1-methylethanol;Isopral;Trichloro-2-propanol;Trichloroisopropanol;1,1,1-TRICHLOROISOPROPANOL
• CAS NO: 76-00-6
• Molecular Formula: C₃H₅Cl₃O
• Molecular Weight: 163.43
• EINECS: 200-924-6
• Mol File: 76-00-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 50.5°C
• Boiling Point: 229.48°C (rough estimate)
• Flash Point: 82.2°C
• Appearance: /
• Density: 1.5578 (rough estimate)
• Vapor Pressure: 0.655mmHg at 25°C
• Refractive Index: 1.4890 (estimate)
• CAS DataBase Reference: 1,1,1-TRICHLORO-2-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-TRICHLORO-2-PROPANOL(76-00-6)
• EPA Substance Registry System: 1,1,1-TRICHLORO-2-PROPANOL(76-00-6)

Safety Data

• Hazardous Substances Data: 76-00-6(Hazardous Substances Data)

Usage

General Description

1,1,1-Trichloro-2-propanol is a chemical compound that is used in various industrial processes, such as as a solvent, an intermediate in the synthesis of other chemicals, and as a chemical intermediate for agricultural products. It is also commonly used in the production of pharmaceuticals, pesticides, and other organic compounds. This chemical has been found to have toxic effects on aquatic organisms and may cause long-term adverse effects in the environment. Therefore, it is important to handle and dispose of 1,1,1-Trichloro-2-propanol with caution in order to minimize its impact on the environment and human health.

InChI:InChI=1/C3H5Cl3O/c1-2(7)3(4,5)6/h2,7H,1H3

Upstream product

• 64-17-5 ethanol 
• 918-00-3 1,1,1-trichloroacetone 
• 555-75-9 aluminum ethoxide 
• 56-23-5 tetrachloromethane 
• 75-77-4 chloro-trimethyl-silane 
• 75-07-0 acetaldehyde 
• 108-05-4 vinyl acetate 
• 67-66-3 chloroform 
• 75-87-6 chloral 
• 300-57-2 allylbenzene 
• 1184-58-3 dimethylaluminum chloride 
• 542-10-9 ethylidene diacetate 
• 917-64-6 methyl magnesium iodide 
• 5764-62-5 tributyl-trichloromethyl-stannane 

Downstream Products

• 7737-40-8 ethyl 2-ethoxypropionate 
• 918-00-3 1,1,1-trichloroacetone 
• 849585-22-4 LACTIC ACID 
• 75-07-0 acetaldehyde 
• 563-58-6 1,1-dichloropropene 
• 64-18-6 formic acid 
• 7623-09-8 2-chloropropionyl chloride 
• 21400-25-9 1,1,2-trichloropropene 
• 78049-86-2 1,1,1-trichloroisopropyl α-chloropropionate 
• 513-88-2 1,1-Dichloroacetone 
• 781-35-1 1,1-diphenylacetone 

Relevant articles and documents

β-siloxy-α-haloketones through highly diastereoselective single and double mukaiyama aldol reactions

Double-action haloketones: A super silyl group enabled the first highly diastereoselective Mukaiyama aldol reactions of α-chloro- and α-fluoroketones with a wide range of aldehydes, providing anti-β-siloxy-α-haloketones. This process is compatible with one-pot double-aldol methodology and allows for rapid access to new halogen-modified polyketide fragments bearing up to four contiguous stereocenters (see scheme). Copyright

EINTOPFSYNTHESE TRICHLOROMETHYLSUBSTITUIERTER ALKOHOLE

A new one-pot synthesis of alcohols RCH(OH)CCl3 starting from CCl4, Me3SiCl, Mg and aldehydes RCHO is described.

AN UNUSUAL REACTION OF TRICHLOROMETHANE WITH ACYLALS IN THE INTERPHASE CATALYSIS CONDITIONS.

Aldehyde diacetates ract with trichloromethane in the standard interphase catalysis conditions to form α-trichloromethylcarbinols or their acetates depending on temperature and time of the reaction.