760197-72-6

Basic information

• Product Name: 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester
• Synonyms: 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester
• CAS NO: 760197-72-6
• Molecular Weight: 418.576
• Mol File: 760197-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester(760197-72-6)
• EPA Substance Registry System: 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester(760197-72-6)

Safety Data

• Hazardous Substances Data: 760197-72-6(Hazardous Substances Data)

Upstream product

• 83841-91-2 (E)-2-methyl-2-pentenoyl chloride 
• 221099-71-4 exo-10,10-diphenyl-10-hydroxymethyl-7,7-dimethylbicyclo[2.2.1]heptane-2-ol 

Downstream Products

• 1030379-39-5 (2R,3S)-1-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-ethyl-2-methylaziridine-2-carboxylic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 

Relevant articles and documents

On the scope of diastereoselective aziridination of various chiral auxiliaries derived N- and O-enones with N-aminophthalimide in the presence of lead tetraacetate

The treatment of a range of N- and O-enones derived from various camphor-based chiral auxiliaries A-D with N-aminophthalimide in the presence of lead tetraacetate is described. In general, N-phthalimidoaziridines were obtained with high diastereoselectivities (up to 98% de) and chemical yields (up to 95%) when 10,10-diphenyl-2,10-camphanediol A derived O-enones with a range of substituents were used under the same reaction conditions. Excellent stereoselectivity was obtained when the N-tosyl camphorpyrazolidinone E derived acrylate was used. The absolute configuration of the new stereogenic center(s) of the major diastereomer was established by X-ray crystallographic analysis. Chiral auxiliary cleavage was achieved under mild reaction conditions. A model to explain the stereochemical induction is also proposed.