83841-91-2

Basic information

• Product Name: (E)-2-methyl-2-pentenoyl chloride
• CAS NO: 83841-91-2
• Molecular Weight: 132.59
• Mol File: 83841-91-2.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: (E)-2-methyl-2-pentenoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-methyl-2-pentenoyl chloride(83841-91-2)
• EPA Substance Registry System: (E)-2-methyl-2-pentenoyl chloride(83841-91-2)

Safety Data

• Hazardous Substances Data: 83841-91-2(Hazardous Substances Data)

Upstream product

• 16957-70-3 2-methylpent-2-enoic acid 
• 1567-14-2 methyl (2E)-2-methyl-2-pentenoate 
• 133181-02-9 3-hydroxy-2-methylene-pentanoic acid methyl ester 
• 1838-77-3 4-methyl-5-hexen-3-ol 
• 623-36-9 (E)-2-methylpent-2-enal 
• 146984-85-2 ethyl (E)-2-iodo-2-pentenoate 
• 55314-57-3 ethyl pent-2-ynoate 
• 159999-59-4 2-(acetoxyethylmethyl)acrylic acid methyl ester 
• 1617-40-9 ethyl (E)-2-methyl-2-pentenoate 

Downstream Products

• 90936-96-2 2,3-dihydro-2-ethyl-3-methyl-5-ethoxycarbonyl-6-phenyl-4-pyrone 
• 96623-45-9 2-methyl-4'-isopropyl-2-pentenoyl anilide 
• 1316008-82-8 (Z)-N-trityl-2-methyl-3-pentenamide 
• 1316008-83-9 (E)-N-trityl-2-methyl-2-pentenamide 
• 760197-72-6 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 613672-55-2 trans-2-benzyl-3-ethyl-4-methylisoxazolidin-5-one 
• 613672-55-2 trans-2-benzyl-3-ethyl-4-methylisoxazolidin-5-one 

Relevant articles and documents

Palladium-Catalyzed Regioselective C-H Functionalization/Annulation Reaction of Amides and Allylbenzenes for the Synthesis of Isoquinolinones and Pyridinones

A regioselective C-H functionalization/annulation reaction of N-sulfonyl amides and allylbenzenes through a palladium-catalyzed C(sp2)-H allylation/aminopalladation/β-H elimination/isomerization sequence has been reported. Various aryl and alkenyl carboxamides are found to be efficient substrates to construct isoquinolinones and pyridinones in up to 96% yield. Using ambient air as the terminal oxidant is another advantage regarding environmental friendliness and operational simplicity.

Nucleophilic halo-michael addition under lewis-base activation

A simple and general conjugate nucleophilic halogenation is presented. The THTO/halosilane combination has shown the ability to act as a nucleophilic halide source in the conjugate addition to a variety of Michael acceptors. In addition, a straightforward diastereoselective halogen installation using α,β-unsaturated acyloxazolidinones as platforms has been developed.

Catalytic Enantioselective Nazarov Cyclization

A detailed account of an asymmetric Nazarov cyclization that leads to α-hydroxycyclopentenones bearing either vicinal, all-carbon quaternary centers, or vicinal quaternary and tertiary centers is given. The all-aliphatic examples represent the greatest challenge, as the dienone starting materials are not activated toward cyclization by an aryl group. The rational design and optimization of the substrates in parallel with optimization of the chiral Br?nsted acid catalyst is also described, as well as a series of diastereoselective transformations of a fully substituted cyclopentenone product.