76228-02-9Relevant articles and documents
Zinc metal-promoted nucleophilic addition of nonactivated alkyl iodides to aromatic aldimines in the presence of chlorotrimethylsilane in ethyl acetate-DMI
Iwai, Toshiyuki,Ito, Takatoshi,Mizuno, Takumi,Ishino, Yoshio
, p. 1083 - 1086 (2004)
A variety of aromatic aldimines react with nonactivated alkyl iodides in the presence of zinc powder and a catalytic amount of chlorotrimethylsilane (TMSCl) in ethyl acetate-DMI to afford the corresponding α- alkylbenzylamine derivatives in good to excellent yields.
A versatile catalyst for reductive animation by transfer hydrogenation
Wang, Chao,Pettman, Alan,Basca, John,Xiao, Jianliang
supporting information; experimental part, p. 7548 - 7552 (2010/12/19)
An iridium catalyst enables the reductive amination of carbonyl groups with unprecedented substrate scope, selectivity, and activity using formic acid as the hydrogen source (see scheme) The catalyst system provides significant improvement over commonly used boron hydrides.
The synthesis of β-lactams via a one-pot Reformatsky reaction of imines promoted by Zn/Cp2TiCl2 (cat.)
Chen, Lei,Zhao, Gang,Ding, Yu
, p. 2611 - 2614 (2007/10/03)
In the presence of Zn/Cp2TiCl2 (cat.) α-bromoacetates, γ-bromocrotonates or α-bromomethylacrylates react with imines in one-pot to form β-lactams, 3-vinyl-β-lactams or α-methylene-γ-lactams, respectively, at room temperature without