772-80-5Relevant articles and documents
Tetrahydrocoptisine derivative and applications thereof
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Paragraph 0422; 0423; 0424, (2016/10/08)
The present invention relates to a compound as shown in a formula (VII), a preparation method and applications thereof in medicines. In particular, the present invention relates to a derivative of the compound as shown in the formula (VII), a preparation method, and the applications of the derivative used as a therapeutic agent in prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, II-type diabetes, hyperglycemia, obesity or insulin resistance syndrome and metabolic syndrome. The compound disclosed by the present invention can also reduce total cholesterol, LDL-cholesterol and triglyceride, and increases expression of a liver LDL receptor and decreases expression of PCSK9.
From homogeneous to heterogeneous catalysis of the three-component coupling of oxysulfonyl azides, alkynes, and amines
Yang, Tao,Cui, Hao,Zhang, Changhe,Zhang, Li,Su, Cheng-Yong
, p. 3131 - 3138 (2013/10/21)
A reliable procedure for the synthesis of oxysulfonyl azides has been developed and applied to the three-component coupling reactions of azides, alkynes, and amines catalyzed homogeneously by CuI, which led to the formation of N-oxysulfonyl amidines with
