77253-67-9 Usage
Chemical Properties
clear colorless liquid
Uses
Recent uses include a gas-phase study of the silaformamide ion and an investigation of substituent effects in photosolvolysis.
General Description
2,2,2-Trifluoroethanol-d3 (TFEd3) is 2,2,2-trifluoroethanol in which hydrogen of the –OH group is substituted with deuterium. It is a commonly used 1H NMR and 13C NMR solvent.
Check Digit Verification of cas no
The CAS Registry Mumber 77253-67-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,5 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77253-67:
(7*7)+(6*7)+(5*2)+(4*5)+(3*3)+(2*6)+(1*7)=149
149 % 10 = 9
So 77253-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C2H3F3O/c3-2(4,5)1-6/h6H,1H2/i1D2,6D
77253-67-9Relevant articles and documents
Simple and efficient catalytic reaction for the selective deuteration of alcohols
Khaskin, Eugene,Milstein, David
, p. 448 - 452 (2013/08/25)
A highly efficient system for the catalytic deuteration of α and β CH bonds of primary and secondary alcohols has been developed. The deuterium source is D2O. Together with the low catalyst loadings and the simple experimental setup, the reaction has direct application to the synthesis of bioactive isotopologues and the direct synthesis of fully deuterated substrates, such as ethanol-d6. The current system represents a significant advance in practicality for homogeneous metal catalyzed systems that carry out H/D exchange in organic substrates with water.