773097-04-4

Basic information

• Product Name: 2-(2-broMo-4-fluorophenyl)-1,3-dioxolane
• Synonyms: 2-(2-broMo-4-fluorophenyl)-1,3-dioxolane
• CAS NO: 773097-04-4
• Molecular Formula: C₉H₈BrFO₂
• Molecular Weight: 247.0610232
• Mol File: 773097-04-4.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(2-broMo-4-fluorophenyl)-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-broMo-4-fluorophenyl)-1,3-dioxolane(773097-04-4)
• EPA Substance Registry System: 2-(2-broMo-4-fluorophenyl)-1,3-dioxolane(773097-04-4)

Safety Data

• Hazardous Substances Data: 773097-04-4(Hazardous Substances Data)

Usage

General Description

2-(2-bromo-4-fluorophenyl)-1,3-dioxolane is a chemical compound with the molecular formula C9H7BrFO2. It is a heterocyclic organic compound that consists of a dioxolane ring with bromine and fluorine substituted phenyl groups attached to it. 2-(2-bromo-4-fluorophenyl)-1,3-dioxolane is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, it is also utilized in the production of various other organic compounds, such as pesticides and herbicides. The chemical properties and structure of 2-(2-bromo-4-fluorophenyl)-1,3-dioxolane make it an important building block in the manufacturing of a wide range of products.

Upstream product

• 59142-68-6 2-bromo-4-fluorobenzaldehyde 
• 107-21-1 ethylene glycol 

Downstream Products

• 1226773-35-8 C₁₆H₁₅BrO₃ 
• 89226-83-5 4-fluoro phthalaldehyde 
• 1258512-11-6 (E)-3-(2-(1,3-dioxolan-2-yl)-5-fluorophenyl)-1-(4-chlorophenyl)prop-2-en-1-one 
• 1258512-12-7 (E)-2-(3-(4-chlorophenyl)-3-oxoprop-1-enyl)-4-fluorobenzaldehyde 
• 1258512-43-4 2'-(4-chlorobenzoyl)-5,6'-difluoro-1,2'-spirobi[indene]-1,3-dione 
• 1258512-09-2 (E)-3-(2-(1,3-dioxolan-2-yl)-5-fluorophenyl)-1-phenylprop-2-en-1-one 
• 1258512-10-5 (E)-4-fluoro-2-(3-oxo-3-phenylprop-1-enyl)benzaldehyde 
• 1258512-08-1 2-(1,3-dioxolan-2-yl)-5-fluorobenzaldehyde 

Relevant articles and documents

Near-Unity Triplet Generation Promoted via Spiro-Conjugation

An intersystem crossing (ISC) rate constant of 1.0×1011 s?1 was previously registered with a spiro-bis-benzophenone scaffold. Triplet generation efficiency could be further enhanced by stabilizing the spiro-charge-transfer (CT) state

Efficient synthesis of dibenzazepine lactams via a sequential Pd-catalyzed amination and aldol condensation reaction

A simple and efficient reaction was developed for the synthesis of dibenzazepine lactam derivatives. The core 7-membered azepine ring was formed by a stepwise sequence involving a palladium-catalyzed amination and an aldol condensation.

Catalytic Dibenzocyclooctene Synthesis via Cobalt(III)–Carbene Radical and ortho-Quinodimethane Intermediates

The metalloradical activation of ortho-benzallylaryl N-tosyl hydrazones with [Co(TPP)] (TPP=tetraphenylporphyrin) as the catalyst enabled the controlled exploitation of the single-electron reactivity of the redox non-innocent carbene intermediate. This method offers a novel route to prepare eight-membered rings, using base metal catalysis to construct a series of unique dibenzocyclooctenes through selective Ccarbene?Caryl cyclization. The desired eight-membered-ring products were obtained in good to excellent yields. A large variety of aromatic substituents are tolerated. The proposed reaction mechanism involves intramolecular hydrogen atom transfer (HAT) to CoIII–carbene radical intermediates followed by dissociation of an ortho-quinodimethane that undergoes 8π cyclization. The mechanism is supported by DFT calculations, and the presence of radical-type intermediates was confirmed by trapping experiments.