77679-10-8

Basic information

• Product Name: Diethoxyphosphinyl thioamide
• Synonyms: Diethoxyphosphinyl thioamide;diethyl (2-amino-2-thioxoethyl)phosphonate;2-diethoxyphosphorylethanethioamide
• CAS NO: 77679-10-8
• Molecular Formula: C₆H₁₄NO₃PS
• Molecular Weight: 211.22
• Mol File: 77679-10-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Diethoxyphosphinyl thioamide(CAS DataBase Reference)
• NIST Chemistry Reference: Diethoxyphosphinyl thioamide(77679-10-8)
• EPA Substance Registry System: Diethoxyphosphinyl thioamide(77679-10-8)

Safety Data

• Hazard Codes: T
• Statements: 25-36
• Safety Statements: 26-45
• Hazardous Substances Data: 77679-10-8(Hazardous Substances Data)

Upstream product

• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 107-56-2 O,O-diisopropyl hydrogen phosphorodithioate 

Downstream Products

• 1620088-78-9 4-[4-(dimethylamino)phenyl]-2-ethoxy-2,5-dihydro-1,5,2-benzothiazaphosphepine-3-carbothioamide 2-oxide 
• 1620088-73-4 2-ethoxy-4-(2-hydroxyphenyl)-2,5-dihydro-1,5,2-benzothiazaphosphepine-3-carbothio-amide 2-oxide 
• 1062508-50-2 2-chloro-3-[(3-chloro-2-quinoxalinyl)-thio]quinoxaline 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 77679-20-0 p-phenylenebis-1-<2-(diethylphosphono)acetamidine>> dihydroiodide 
• 77679-19-7 N¹-(2-methoxyphenyl)-2-(diethylphosphono)acetamidine hydroiodide 
• 77679-18-6 N¹-anilino-2-(diethylphosphono)acetamidine hydroiodide 
• 77679-12-0 N¹-benzyl-2-(diethylphosphono)acetamidine hydroiodide 

Relevant articles and documents

Phosphorylated arginine analogue, synthesis method and application thereof

The invention discloses a phosphorylated arginine analogue, a synthesis method and application thereof, and relates to phosphorylated arginine analogues. The phosphorylated arginine analogue is characterized in that a phosphoryl acetamidine structure is adopted as a main body; the phosphorylated arginine analogue can be utilized as hapten for preparing an antibody used for recognizing pArg on protein; the antibody prepared from the phosphorylated arginine analogue has specificity of recognizing pArg, and cross reactivity with other common phosphorylation modification forms in protein is low; besides, a mouse polyclonal antibody prepared from the phosphorylated arginine analogue is mainly of IgG2a type, and can be used for screening monoclonal antibodies; and the phosphorylated arginine analogue can be further utilized as an inhibitor of protein phosphorylated arginine esterase, utilized as a biochemical reagent for studying biological functions of the protein phosphorylated arginine esterase, or a lead compound for medicinal development aimed at the protein phosphorylated arginine esterase.

Phosphorus-substituted carbothioamides

A facile procedure was developed for the synthesis of phosphorus- substituted carbothioamides by the reaction of the corresponding nitriles with O,O-diisopropyl dithiophosphate in the presence of methanol. The structural features and hydrogen bonding in c

A convergent synthesis of Ro24-5913, a novel leukotriene D4 antagonist

A new and convergent synthesis of the leukotriene D4 antagonist Ro24-5913 (9) has been developed that can serve both for technical production and combinatorial structure optimization. The synthesis of 6, achieved in 90% yield, is described. The conversion of 6 to 9 has been disclosed previously.