77784-22-6

Basic information

• Product Name: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dime thoxy-7-methyl-
• Synonyms: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dime thoxy-7-methyl-;DEHYDROCREBANINE
• CAS NO: 77784-22-6
• Molecular Formula: C20H19NO4
• Molecular Weight: 337.37
• Mol File: 77784-22-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 547.6°C at 760 mmHg
• Flash Point: 167.2°C
• Appearance: /
• Density: 1.312g/cm³
• Vapor Pressure: 4.8E-12mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dime thoxy-7-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dime thoxy-7-methyl-(77784-22-6)
• EPA Substance Registry System: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dime thoxy-7-methyl-(77784-22-6)

Safety Data

• Hazardous Substances Data: 77784-22-6(Hazardous Substances Data)

Usage

Occurrence

A constituent of the basic extract of Stephania sasakii, this derivative of crebanine has been obtained as colourless crystals from EtOH.

InChI:InChI=1/C20H19NO4/c1-21-7-6-11-8-16-20(25-10-24-16)18-12-4-5-15(22-2)19(23-3)13(12)9-14(21)17(11)18/h4-5,8-9H,6-7,10H2,1-3H3

Upstream product

• 517-62-4 (-)-crebanine 
• 77784-23-7 stesakine 
• 188922-54-5 5-[1-(6-Bromo-2,3-dimethoxy-phenyl)-meth-(Z)-ylidene]-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinoline-6-carboxylic acid ethyl ester 
• 188922-51-2 1-(6-bromo-2,3-dimethoxybenzyl)-6,7-methylenedioxy-3,4-dihydroisoquinoline 
• 188922-45-4 2-(6-bromo-2,3-dimethoxyphenyl)-N-(3,4-methylenedioxyphenethyl)acetamide 
• 107290-26-6 2-(6-Bromo-2,3-dimethoxyphenyl)acetyl chloride 
• 188922-58-9 9,10-Dimethoxy-5,6-dihydro-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline-7-carboxylic acid ethyl ester 
• 517-62-4 Crebanine 
• 186581-53-3 diazomethane 

Relevant articles and documents

Synthesis and structure-activity relationships of a series of aporphine derivatives with antiarrhythmic activities and acute toxicity

Some aporphine alkaloids, such as crebanine, were found to present arrhythmic activity and also higher toxicity. A series of derivatives were synthesized by using three kinds of aporphine alkaloids (crebanine, isocorydine, and stephanine) as lead compound

THE ALKALOIDS OF STEPHANIA SASAKII: STRUCTURE OF FIVE NEW ALKALOIDS

Five new alkaloids, dehydrocrebanine, 4,5-dioxodehydrocrebanine, stesakine, dehydrostesakine, bisaknidinine and four known alkaloids, lirodenine, lanuginosine, 1-tetrahydropalmatine, d-isocorydine with a few alkaloids of unknown structure were newly isolated from Stephania sasakii.The structures of the new alkaloids were determined from spectral data and chemical evidence. - Key Word Index : Stephania sasakii; Menispermaceae; dehydrocrebanine; 4,5-dioxodehydrocrebanine; bisaknadinine; stesakine; dehydrostesakine.