77855-51-7Relevant articles and documents
Amides in one pot from Carboxylic Acids and Amines via Sulfinylamides
Bai, Jianfei,Zambron, Bartosz K.,Vogel, Pierre
supporting information, p. 604 - 607 (2014/04/03)
An efficient method has been developed for the direct amidification of carboxylic acids via sulfinylamides preformed in situ by the reaction of pure amines with prop-2- ene-1-sulfinyl chloride. The method can be applied to aliphatic acids, including pivalic acid, aromatic acids, and primary and secondary amines. It is compatible with acids bearing unprotected alcohol, phenol, and ketone moieties and applicable to the synthesis of peptides. It does not induce their a-epimerization.
Synthesis of β-amino alcohols via the reduction of lactamides derived from ethyl (2S)-lactate with borane-methyl sulfide
Lewis, Frank W.,Eichler, Matthias C.,Grayson, David H.
experimental part, p. 1923 - 1928 (2009/12/29)
Reactions of ethyl (2S)-lactate with various amines affords lactamides that are reduced with borane-methyl sulfide in the presence of boron trifluoride etherate to generate enantiomerically pure β-amino alcohols in good yield. Georg Thieme Verlag Stuttgart.
ASYMMETRIC CATALYTIC HYDROGENATIONS OF CHIRAL alpha -KETO AMIDES.
Harada,Munegumi
, p. 3203 - 3209 (2007/10/02)
Asymmetric catalytic hydrogenations of chiral pyruvamides were carried out using palladium on charcoal (Pd-C) as a catalyst to give lactamides with the diastereoisomeric purities (d. p. ) of up to 62%. It was found that there was a linear correlation betw
