78138-99-5Relevant articles and documents
Synthesis of polyhydroxylated quinolizidine and indolizidine scaffolds from sugar-derived lactams via a one-pot reduction/Mannich/Michael sequence
Szczesniak, Piotr,Stecko, Sebastian,Maziarz, Elzbieta,Staszewska-Krajewska, Olga,Furman, Bartlomiej
, p. 10487 - 10503 (2015/02/19)
A direct approach to the synthesis of indolizidine and quinolizidine scaffolds of iminosugars is described. The presented strategy is based on a one-pot sugar lactam reduction with Schwartz's reagent followed by a diastereoselective Mannich/Michael tandem reaction of the resulting sugar imine with Danishefsky's diene. The stereochemical course of the investigated reaction has been explained in detail. The obtained bicyclic products are attractive building blocks for the synthesis of various naturally occurring polyhydroxylated alkaloids and their derivatives.
A new DNA building block, 4′-selenothymidine: Synthesis and modification to 4′-seleno-AZT as a potential anti-HIV agent
Alexander, Varughese,Choi, Won Jun,Chun, Jeongha,Kim, Hea Ok,Jeon, Ji Hye,Tosh, Dilip K.,Lee, Hyuk Woo,Chandra, Girish,Choi, Jungwon,Jeong, Lak Shin
supporting information; experimental part, p. 2242 - 2245 (2010/08/05)
The first synthesis of 4′-selenothymidine (1), a novel DNA building block, and 4′-seleno-AZT (2) was accomplished from 2-deoxy-d-ribose via stereoselective formation of 2-deoxy-4-seleno-d-furanose 17 and a Pummerer-type base condensation as key steps. 4′-
Synthesis of the chiral CD rings of paclitaxel from 2-deoxy-D-ribose: Novel 1,2-addition of a dienolate to a chiral ketone
Takahashi, Takashi,Hirose, Yoichiro,Iwamoto, Hajime,Doi, Takayuki
, p. 5742 - 5743 (2007/10/03)
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