78315-04-5

Basic information

• Product Name: (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride
• Synonyms: (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride
• CAS NO: 78315-04-5
• Molecular Weight: 366.931
• Mol File: 78315-04-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride(78315-04-5)
• EPA Substance Registry System: (E)-4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl chloride(78315-04-5)

Safety Data

• Hazardous Substances Data: 78315-04-5(Hazardous Substances Data)

Upstream product

• 71441-28-6 TTNPB 
• 17610-21-8 1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphth-2-yl)ethanone 
• 69251-24-7 [1-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-ethyl]-triphenylphosphonium bromide 
• 69251-25-8 5,6,7,8-tetrahydro-α,5,5,8,8-pentamethyl-2-naphthalene methanol 
• 69251-26-9 2-(bromoethyl)-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene 
• 71441-09-3 AGN 190316 
• 16173-52-7 4-formylbenzoyl chloride 
• 85209-05-8 Triphenyl-[1-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-ethylidene]-λ⁵-phosphane 

Downstream Products

• 71441-38-8 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzoic acid isopropyl ester 
• 71441-29-7 p-<(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl>-benzoic acid monoethylamide 
• 82205-77-4 (E)-5-<4-<<4-<2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-methylethenyl>benzoyl>oxy>butyl>-2-thiouracil 

Relevant articles and documents

A-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF

Analogs of 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1 - propenyl]benzoic acid and methods of manufacture and use thereof, such as for use in cancer prevention and treatment.

Arotinoids, a new class of highly active retinoids

The synthesis and biological activity of new aromatic retinoids are reported. The most active ones belong to a chemical class of compounds, which we have termed 'arotinoids'. For the compound p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-propenyl)]-benzoic acid ethyl ester, a therapeutic potency in the antipapilloma test was found which exceeds that of retinoic acid by a factor of 8000, while the concurrently observed toxic hypervitaminosis A effects are only increased by a factor of 800. The structural relationship of the arotinoids with retinoic acid is demonstrated; the arotinoids contain the retinoic acid carbon skeleton in a fixed cisoid geometric conformation.