78877-72-2Relevant articles and documents
CHEMISTRY OF 2-BROMO-2-METHYLPROPANAMIDES. SYNTHESIS AND SOLVOLYTIC BEHAVIOUR OF OXAZOLIDINONES AND SPIRO-OXAZOLIDINONES
Scrimin, Paolo,Cavicchioni, Giorgio,D'Angeli, Ferruccio,Goldblum, Amiram,Maran, Flavio
, p. 43 - 48 (2007/10/02)
The base-promoted reaction of 2-bromo-2-methylpropanamides (1) with 5-, 6-, and 7-membered lactams (2) affords spiro-oxazolidinones (3).The latter compounds are hydrolysed under acidic conditions to yield the ω-aminoester amides (7).The solvolytic behaviour of some monocyclic oxazolidinones obtained upon reaction of common amides with 2-bromoamides (1) is also reported.