79050-23-0 Usage
Uses
Different sources of media describe the Uses of 79050-23-0 differently. You can refer to the following data:
1. Linoleic acid-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of linoleic acid by GC- or LC-mass spectrometry. Linoleic acid is a PUFA found in plant tissues and most cooking oils. Deficiencies in the essential fatty acid linoleic acid are linked to coronary heart disease, growth retardation, and allergies. Linoleic acid can be metabolized by prostaglandin H synthases (PGHS) to form 9- and 13-HODE. The Km is 12 μM for human PGHS-1 and 27 μM for PGHS-2.[Cayman Chemical]
2. Linoleic Acid-d4 is a labeled activator of PPAR.
Check Digit Verification of cas no
The CAS Registry Mumber 79050-23-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,0,5 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 79050-23:
(7*7)+(6*9)+(5*0)+(4*5)+(3*0)+(2*2)+(1*3)=130
130 % 10 = 0
So 79050-23-0 is a valid CAS Registry Number.
79050-23-0Relevant articles and documents
Synthesis of linoleic acids combinatorially labeled at the vinylic positions as substrates for lipoxygenases
Meyer, Matthew P.,Klinman, Judith P.
, p. 3600 - 3603 (2008/09/19)
Mammalian lipoxygenases have been implicated in a number of inflammation-related human diseases. Soybean lipoxygenase-1 is the archetypical example of known lipoxygenases. Here we report the synthesis of linoleic acid and (11,11)-d2-linoleic acid which are combinatorially labeled at the vinylic positions (9, 10, 12, and 13). Combinatorial labeling schemes allow for the simultaneous determination of KIEs in enzymatic reactions using NMR. Substrates are, thus, available as probes of detailed mechanism in kinetic isotope effect (KIE) studies of lipoxygenases.
