79418-71-6

Basic information

• Product Name: 4-(benzyloxy)-2-hydroxy-5-methoxybenzaldehyde
• Synonyms: 4-(benzyloxy)-2-hydroxy-5-methoxybenzaldehyde
• CAS NO: 79418-71-6
• Molecular Weight: 258.274
• Mol File: 79418-71-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(benzyloxy)-2-hydroxy-5-methoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-2-hydroxy-5-methoxybenzaldehyde(79418-71-6)
• EPA Substance Registry System: 4-(benzyloxy)-2-hydroxy-5-methoxybenzaldehyde(79418-71-6)

Safety Data

• Hazardous Substances Data: 79418-71-6(Hazardous Substances Data)

Upstream product

• 51061-83-7 2,4-dihydroxy-5-methoxybenzaldehyde 
• 100-39-0 benzyl bromide 

Downstream Products

• 921197-12-8 (5-benzyloxy-2-formyl-4-methoxyphenoxy)acetic acid ethyl ester 
• 656836-79-2 14-(4-hydroxy-3-methoxyphenyl)-3,11-dihydroxy-2,12-dimethoxy-8,9-dihydro-6H-chromeno[4',3':4,5]pyrrolo[2,1-a]isoquinolin-6-one 
• 97614-65-8 lamellarin D 
• 190278-32-1 3,10-Bis-benzyloxy-13-(4-benzyloxy-3-methoxy-phenyl)-2,11-dimethoxy-5-oxa-6b-aza-dibenzo[a,i]fluoren-6-one 

Relevant articles and documents

Construction of Pentacyclic Lamellarin Skeleton via Grob Reaction: Application to Total Synthesis of Lamellarins H and D

An efficient construction of phenyl-substituted coumarin-pyrrole-isoquinoline-fused pentacycle via base-promoted Grob-type coupling of 3-nitrocoumarin and papaverine in a sealed tube is reported. This reaction is further applied to the total synthesis of lamellarin H in three linear steps and lamellarin D in eight linear steps with overall yields of 31% and 14%, respectively.

NEW PHARMACEUTICAL COMPOUNDS

Compounds of formula (I), wherein R1-R4, X, Y and Z are as defined in claims, exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors.