80015-61-8

Basic information

• Product Name: 5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)-N⁴-benzoyl cytidine
• CAS NO: 80015-61-8
• Molecular Weight: 769.851
• Mol File: 80015-61-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)-N⁴-benzoyl cytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)-N⁴-benzoyl cytidine(80015-61-8)
• EPA Substance Registry System: 5'-O-dimethoxytrityl-2'-O-(4-methoxybenzyl)-N⁴-benzoyl cytidine(80015-61-8)

Safety Data

• Hazardous Substances Data: 80015-61-8(Hazardous Substances Data)

Upstream product

• 65-46-3 CYTIDINE 
• 98-88-4 benzoyl chloride 
• 2746-25-0 p-Methoxybenzyl bromide 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 80015-59-4 2'-O-(4-methoxybenzyl)-N⁴-benzoylcytidine 

Downstream Products

• 80015-65-2 Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(4-methoxy-benzyloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester 
• 80015-64-1 Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(4-methoxy-benzyloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester 

Relevant articles and documents

Synthesis of Ribooligonucleotides Using the 4-Methoxybenzyl Group as a New Protecting Group for the 2'-Hydroxyl Group

The 4-methoxybenzyl group was introduced to protect the 2'-hydroxyl group of uridine, cytidine, and N2-benzoylguanosine by treatment of 2',3'-O-(dibutylstannylene)uridine or NaH-treated nucleosides with 4-methoxybenzyl bromide.The 2'-O-(4-methoxybenzyl)nucleosides can be used as useful starting materials for the synthesis of 3',5'-linked ribooligonucleotides.The 4-methoxybenzyl group was removed rapidly from the ribooligonucleotides by treatment with triphenylmethyl fluoroborate, and the completely deblocked ribooligonucleotides were characterized by enzymatic hydrolysis.