811-62-1

Basic information

• Product Name: CHLORO(DIMETHYL)PHOSPHINE
• Synonyms: (CH3)2PCl;Phosphinous chloride, dimethyl-;CHLORO(DIMETHYL)PHOSPHINE;DIMETHYLCHLOROPHOSPHINE;DIMETHYLPHOSPHINOUS CHLORIDE;Dimethylchlorophosphine,min.97%;Dimethylchlorophosphine, min. 97%;Dimethylphosphine chloride
• CAS NO: 811-62-1
• Molecular Formula: C₂H₆ClP
• Molecular Weight: 96.5
• EINECS: 212-372-3
• Product Categories: organophosphine halide;Achiral Phosphine;Alkyl Phosphine;P-Cl
• Mol File: 811-62-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: -4-0℃
• Boiling Point: 76-77°C
• Flash Point: -18°C
• Appearance: Colorless/Liquid
• Density: 1,22 g/cm3
• Vapor Pressure: 387mmHg at 25°C
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: CHLORO(DIMETHYL)PHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: CHLORO(DIMETHYL)PHOSPHINE(811-62-1)
• EPA Substance Registry System: CHLORO(DIMETHYL)PHOSPHINE(811-62-1)

Safety Data

• Statements: 17-34
• Safety Statements: 16-26-36/37/39-45
• RIDADR: 2845
• HazardClass: 4.2
• PackingGroup: I
• Hazardous Substances Data: 811-62-1(Hazardous Substances Data)

Usage

General Description

Chloro(dimethyl)phosphine is a chemical compound with the formula (CH3)2PCl. It is a colorless liquid with a strong repugnant smell, and handles moisture and air sensitively. This chemical is widely used as an intermediate in organic synthesis, largely in the pharmaceutical, agrochemical, and other specialty chemicals industries. It is crucial to handle chloro(dimethyl)phosphine safely due to its flammable and corrosive nature, and it can cause severe skin burns and eye damage.

InChI:InChI=1/C2H6ClP/c1-4(2)3/h1-2H3

Upstream product

• 74-87-3 methylene chloride 
• 676-83-5 methyldichlorophosphane 
• 683-84-1 (dimethylamino)dimethylphosphine 
• 3676-91-3 tetramethyldiphosphane 

Downstream Products

• 993-12-4 dimethylphosphinothioic chloride 
• 56918-07-1 C₁₁H₁₇NOP₂S 
• 18629-11-3 benzyldimethylphosphine oxide 
• 56918-08-2 C₁₁H₁₉NO₂P₂S₂ 
• 56918-00-4 C₁₆H₂₂NP₃S 
• 56918-01-5 C₁₆H₂₂NP₃S 
• 683-84-1 (dimethylamino)dimethylphosphine 
• 72337-96-3 C₂₇H₂₇P₃ 
• 33027-76-8 <(Diphenylmethyliden)amino>dimethylphosphin 
• 35449-60-6 dimethyl methylthiophosphinite 
• 72565-28-7 Dimethyl-<2-chlor-phenyl>-phosphin 
• 55590-36-8 (10-TB-5-12)-10,10-dimethyl-2,3-diphenyl-10λ⁵-benzo[d][1,3,2]oxazaphospholo[2,3-b][1,3,2]oxazaphosphole 
• 55590-42-6 5,6,8,8-tetramethyl-2-phenyl-8λ⁵-[1,3,2]oxazaphospholo[2,3-b][1,3,4,2]oxadiazaphosphole 
• 64065-08-3 dmpm 

Relevant articles and documents

Haloalkylation process

A process for the haloalkylation of certain tin, phosphorus and germanium halides is disclosed. The process is carried out typically in a halocarbon solvent at temperatures of less than 0° C. using as the haloalkylating reagent an admixture of a haloalkyl halide and tris(lower alkylamino)phosphine.

Process for making tetramethyldiphosphinomethane

Novel chemical compounds which comprise tetramethyldiphosphinomethane of the formula: and methyllithium-dimethylphosphine of the formula: the latter being an intermediate product. Methyllithium-dimethylphosphine is made by reacting a solution of trimethylphosphine with a solution of alkyllithium in an inert solvent with the exclusion of air and moisture, filtering the resulting white precipitate, washing it with the inert solvent, and drying the washed material. Tetramethyldiphosphinomethane is made by reacting, with agitation, a suspension of methyllithium-dimethylphosphine, or dilithiomethane of the formula Li(CH)2 or magnesiomethane of the formula MgCH2 in an organic solvent with dimethylchlorophosphine and distilling the resulting reaction mixture.