81334-34-1 Usage
Chemical Properties
solid
Uses
Imazapyr is an analytical standard used for proteomics research.
Pharmacology
Imazapyr kills plants by inhibiting acetolactate synthase
(ALS) (I50 = 5 μM), which is the first common enzyme in
the biosynthesis of the branched chain amino acids, valine,
leucine, and isoleucine. Imazapyr is rapidly absorbed
through the leaves of plants. Once it enters the plant,
imazapyr rapidly translocates to the growing points and
growth ceases within 1 day after herbicide application
followed by chlorosis and then necrosis of the growing
points. Total plant death will occur within 2 to 3 weeks
after treatment.
Environmental Fate
Imazapyr is weakly to moderately adsorbed on sandy loam
and silt loam soils. The Freundlich adsorption coefficient ranges from 0 to 7.8 (15). Because imazapyr is a weak acid
and exists in different ionic states, soil pH has an effect on
soil binding properties. The anionic form predominates at
soil pH as low as 5.5, and this form bindsweakly to soil. The
neutral or molecular form is important at soil pH from 4
to 6.5. This form binds to soil organic matter and clay. The
cationic form is important at pH less than 4. Because the
soil is a heterogeneous mixture of acid and base chemical
groups, there may be sites within a particular soil that are
2 to 3 pH units higher or lower than the average pH. The
cationic form will bind tightly to the lower pH components.
Because of these interactions, small decreases in pH below 6 will result in large increases in binding. The half-life of
imazapyr in the soil is 25–142 d (14). Imazapyr remains
in the top 30 cm of the soil with low leaching potential.
The degradation route of imazapyr in the soil has not been
determined.
Metabolism
Plant Metabolism. The selectivity of imazapyr is due to
differential rates and routes of metabolism in tolerant
crops versus susceptible weeds (3). The half-life
of imazapyr in tolerant crops has not been accurately
determined. The metabolic route of imazapyr is not clear.
The parent compound can be metabolized to a tricyclic
compound (33, Fig. 15) in some species, but the primary
metabolite is an imidazopyrrolo-pyridine derivative (34,
Fig. 15). This compound does not inhibit acetolactate
synthase, the target site for the imidazolinones, and it
is immobile in the plant (4).
Animal Metabolism. Metabolism studies in the rat
showed that imazapyr is rapidly excreted in the urine (5).
There was no accumulation of imazapyr or any of its
derivatives in the liver, kidney, muscle, fat, or blood.
Toxicity evaluation
Imazapyr has shown no mutagenic or genotoxic activity
in the Ames assay, mammalian cell gene mutation assay,
in vitro chromosome aberration assay, in vitro unscheduled
DNA synthesis (URS) assay, or the in vivo dominant
lethal assay in male rats.This herbicide also has a low potential for bioaccumulation
in fish.
Check Digit Verification of cas no
The CAS Registry Mumber 81334-34-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,3,3 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81334-34:
(7*8)+(6*1)+(5*3)+(4*3)+(3*4)+(2*3)+(1*4)=111
111 % 10 = 1
So 81334-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H19N3O3/c1-5-9-6-10(13(19)20)11(16-7-9)12-17-14(21)15(4,18-12)8(2)3/h6-8H,5H2,1-4H3,(H,19,20)(H,17,18,21)
81334-34-1Relevant articles and documents
HERBICIDAL COMPOSITIONS
-
, (2022/03/02)
The present invention provides compositions comprising herbicidally active compounds (A) and (B), where (A) represents one or more compounds of the general formula (I) or agrochemically compatible salts thereof [component (A)], and (B) represents one or more herbicides [component (B)]. The application further relates to a method and to the use of the herbicidal composition according to the invention for controlling harmful plants or for regulating growth.
Synthesis method of imazapyracid
-
Paragraph 0024-0025; 0030-0033, (2021/01/11)
The invention relates to a synthesis method of imazapyracid, relates to a preparation method of a compound, and in particular, relates to a production and synthesis method of imazapyracid; the methodis characterized by comprising the steps: taking quinolinic acid as a raw material and reacting with acetic anhydride to generate 2,3-pyridine dicarboxylic anhydride; and under a low-temperature condition, continuously reacting with alcohol to generate a compound represented by a structural formula (I), carrying out a ring closing reaction with 2-amino-2,3-dimethylbutyramide under an alkaline condition, extracting to adjust the pH value, and thus obtaining the imazapyracid product. The method has the advantages that a novel method for obtaining imazapyracid is provided, the route reaction speed is high, the product purity is extremely high, the yield is high, the reaction conditions are mild, isomers are avoided, catalysts are not needed, three wastes are few, the synthesis process is extensive, the reaction conditions are optimized, the reaction equipment cost is reduced, generated products are easy to separate, and the production process is simplified.
Method for Controlling Rust Infections in Leguminous Plants
-
, (2009/06/27)
Method for controlling rust infections in leguminous plants by using heterocyclylcarboxanilides of the formula I where n=0-4; X=C1-C4-haloalkyl; Het=a pyrazole, thiazole or pyridine radical of the formula IIa, IIb or IIc where R1 is C1-C4-alkyl or C1-C4-haloalkyl, R2 is H or halogen, R3 is C1-C4-alkyl or C1-C4-haloalkyl, R4 is C1-C4-alkyl or C1-C4-haloalkyl and R5 is halogen, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-alkylsulfinyl or C1-C4-alkylsulfonyl, mixtures of heterocyclylcarboxanilides of the formula I and a fungicidally active compound II from the group of the azoles, acylalanines, amine derivatives, anilinopyrimidines, dicarboximides, dithiocarbamates, heterocylic compounds, phenylpyrroles, cinnamides, and analogs, or other fungicides according to the description, and also compositions and seed comprising these mixtures.
