81542-54-3

Basic information

• Product Name: 5-CYCLOHEXYL-1H-PYRAZOL-3-AMINE
• Synonyms: 5-CYCLOHEXYL-1H-PYRAZOL-3-AMINE;5-Cyclohexyl-1H-pyrazol-3-ylaMine;1H-Pyrazol-3-aMine, 5-cyclohexyl-
• CAS NO: 81542-54-3
• Molecular Formula: C₉H₁₅N₃
• Molecular Weight: 165.2355
• Mol File: 81542-54-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 381.9 °C at 760 mmHg
• Flash Point: 212.9 °C
• Appearance: /
• Density: 1.143 g/cm³
• Vapor Pressure: 4.93E-06mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-CYCLOHEXYL-1H-PYRAZOL-3-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CYCLOHEXYL-1H-PYRAZOL-3-AMINE(81542-54-3)
• EPA Substance Registry System: 5-CYCLOHEXYL-1H-PYRAZOL-3-AMINE(81542-54-3)

Safety Data

• Hazardous Substances Data: 81542-54-3(Hazardous Substances Data)

Usage

General Description

5-Cyclohexyl-1H-pyrazol-3-amine is a chemical compound with the molecular formula C9H14N4. It is a heterocyclic amine that belongs to the pyrazole class of compounds. This chemical is commonly used in the pharmaceutical industry as a building block for the synthesis of various biologically active molecules, including potential drug candidates. It is also known for its use as a ligand in coordination chemistry and as a reagent in organic synthesis. 5-Cyclohexyl-1H-pyrazol-3-amine has been studied for its potential medicinal properties and has shown promising results in various biological assays, making it an important chemical for drug discovery and development.

InChI:InChI=1/C9H15N3/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h6-7H,1-5H2,(H3,10,11,12)

Upstream product

• 4630-82-4 methyl cyclohexylcarboxylate 
• 62455-70-3 3-cyclohexyl-3-oxopropanenitrile 
• 3289-28-9 ethyl cyclohexanecarboxylate 

Downstream Products

• 133549-60-7 2,6-dicyclohexyl-6,7-dihydro-4H-pyrazolo<1,5-a>pyrrolo<3,4-d>pyrimidine-5,8-dione 

Relevant articles and documents

Nitrogen-containing ring derivative inhibitor as well as preparation method and application thereof

The invention relates to a nitrogen-containing ring derivative inhibitor as well as a preparation method and an application thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method thereof, a pharmaceutical composition containing the compound, and uses of the compound as a P2X3 inhibitor in treatment of P2X3 receptor dysfunction diseases, especially in treatment of neurogenic diseases.

NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS

The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Synthesis and Hypocholesterolemic Activity of 6,7-Dihydro-4H-pyrazolopyrrolopyrimidine-5,8-diones, Novel Inhibitors of AcylCoA:Cholesterol O-Acyltransferase

A novel series of 6,7-dihydro-4H-pyrazolopyrrolopyrimidine-5,8-dione inhibitors of the enzyme acylCoA:cholesterol O-acyltransferase is described.A number of these derivatives were found to be potent modulators of serum lipoprotein levels in