81589-31-3

Basic information

• Product Name: 4-METHYL-N-(NAPHTHALENE-1-CARBONYL)-BENZENESULFONAMIDE
• Synonyms: 4-METHYL-N-(NAPHTHALENE-1-CARBONYL)-BENZENESULFONAMIDE
• CAS NO: 81589-31-3
• Molecular Formula: C₁₈H₁₅NO₃S
• Molecular Weight: 325.3816
• Mol File: 81589-31-3.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-METHYL-N-(NAPHTHALENE-1-CARBONYL)-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-N-(NAPHTHALENE-1-CARBONYL)-BENZENESULFONAMIDE(81589-31-3)
• EPA Substance Registry System: 4-METHYL-N-(NAPHTHALENE-1-CARBONYL)-BENZENESULFONAMIDE(81589-31-3)

Safety Data

• Hazardous Substances Data: 81589-31-3(Hazardous Substances Data)

Upstream product

• 1576-37-0 N-benzyl-p-toluenesulfonamide 
• 90-14-2 1-Iodonaphthalene 
• 70-55-3 toluene-4-sulfonamide 
• 13939-06-5 molybdenum hexacarbonyl 
• 127-65-1 chloroamine-T 
• 66-77-3 1-naphthaldehyde 
• 91-20-3 naphthalene 
• 4083-64-1 Tosyl isocyanate 
• 98-59-9 p-toluenesulfonyl chloride 
• 879-18-5 naphthalene-1-carbonic acid chloride 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 

Downstream Products

• 1360743-68-5 C₂₇H₂₂N₂O₃S 
• 1356832-68-2 C₂₆H₂₅NO₇S 
• 1356832-67-1 3-ethoxycarbonyl-3-ethoxycarbonylmethyl-2-tosyl-5,6-benzo isoindolin-1-one 
• 1267588-24-8 C₂₅H₂₅NO₅S 
• 1379506-01-0 C₂₉H₃₁NO₂SSi 
• 1379505-93-7 C₁₉H₁₇NO₃S 
• 1379506-13-4 N-tosyl-1-naphthimidoyl chloride 

Relevant articles and documents

Chemoselective Cleavage of Acylsulfonamides and Sulfonamides by Aluminum Halides

The chemoselective cleavage of C-N bonds of amides, sulfonamides, and acylsulfonamides by aluminum halides is described. AlCl3and AlI3display complementary reactivities toward N-alkyl and N-acyl moieties. N-Alkylacylsulfonamides, sec

Ruthenium-Catalyzed Synthesis of Isoindolinones via Amide-Directed Addition of Aromatic C-H Bonds to Aldimines

Ruthenium-catalyzed addition of aromatic C-H bonds to aldimines is described. [RuCl2(p-cymene)]2 functions as an efficient catalyst to promote the coupling of aryl amides with aldimines in the presence of a catalytic amount of base to give the corresponding isoindolinone derivatives. The nature of the substituent at the N-atom of the amides is crucial for the efficient conversion of the substrates, and a p-toluenesulfonyl group is the functionality of choice. A variety of amides and aldimines participated in the present Ru-catalyzed reaction to furnish the corresponding isoindolinones in moderate to high yield.

Efficient synthesis of carbon-11 labelled acylsulfonamides using [11C]CO carbonylation chemistry

Herein, a novel method for carbon-11 labeling of acyl sulfonamides by a one-step insertive [11C]CO carbonylative cross-coupling reaction between aryl halides and sulfonamides is presented. Various model compounds as well as drug molecules LY573636 (tasisulam) and ABT-199 were obtained in excellent yields. This method provides a valuable and widely applicable contribution to the continuously expanding radiochemical toolbox for PET research.