816-39-7Relevant articles and documents
Two New Amphiphilic Catalysts for Ester Hydrolysis
Menger, F. M.,Persichetti, R. A.
, p. 3451 - 3452 (1987)
-
Synthesis of α,β-unsaturated epoxy ketones utilizing a bifunctional sulfonium/phosphonium ylide
Eskandari, Roozbeh,Hess, Jeremy P.,Tochtrop, Gregory P.
supporting information, p. 7136 - 7139 (2021/07/28)
Herein, a new protocol for rapid synthesis of α,β-unsaturated epoxy ketones utilizing a bifunctional sulfonium/phosphonium ylide is described. This approach comprises two sequential chemoselective reactions between sulfonium and phosphonium ylides and two distinct aldehydes, which allows for the rapid construction of a variety of unsymmetric α,β-unsaturated epoxy ketones. This methodology allows the rapid construction of the core reactive functionality of a family of lipid peroxidation products, the epoxyketooctadecenoic acids, but can be further broadly utilized as a useful synthon for the synthesis of natural products, particularly those derived from oxidized fatty acids. Accordingly, a protocol utilizing this approach to synthesize the epoxyketooctadecenoic acid family of molecules is described.
1,3-bis(R-group ferrocene)-2-propyl alcohol and synthesis method
-
Paragraph 0027; 0028; 0029; 0036; 0037; 0038; 0045-0047, (2017/04/14)
The invention relates to a synthesis method of 1,3-bis(R-group ferrocene)-2-propyl alcohol (R is C2-C4 alkyl). The synthesis method comprises the following steps: dissolving ferrocene in a solvent; slowly adding a halogenated (or hydroxyl and olefin) compound with the carbon number of 2-4 and a catalyst for reaction; performing washing with water, evaporating the solvent and performing rectification to obtain R-group ferrocene; adding acetone and a solvent in another reactor; slowly adding bromine for reaction for a period of time, and then performing washing with water, evaporating the solvent and performing recrystallization to obtain 1,3-dibromoacetone; carrying out Friedel-Crafts alkylation reaction on the R-group ferrocene and the 1,3-dibromoacetone to obtain 1,3-bis(R-group ferrocene) acetone; adding reducing agents such as sodium borohydride in the 1,3-bis(R-group ferrocene) acetone to obtain the 1,3-bis(R-group ferrocene)-2-propyl alcohol as the product. The synthesized bisferrocene derivative is used in a solid propellant and a burning rate regulator, and cannot migrate easily when reacting with a curing agent.