82231-56-9

Basic information

• Product Name: Benzenamine, 4-(5-phenyl-1H-pyrazol-3-yl)-
• CAS NO: 82231-56-9
• Molecular Formula: C15H13N3
• Molecular Weight: 235.288
• Mol File: 82231-56-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-(5-phenyl-1H-pyrazol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-(5-phenyl-1H-pyrazol-3-yl)-(82231-56-9)
• EPA Substance Registry System: Benzenamine, 4-(5-phenyl-1H-pyrazol-3-yl)-(82231-56-9)

Safety Data

• Hazardous Substances Data: 82231-56-9(Hazardous Substances Data)

Upstream product

• 63532-66-1 3-(4-nitrophenyl)-5-phenyl-1H-pyrazole 
• 5281-18-5 benzaldehyde, hydrazone 
• 99-92-3 p-aminobenzophenone 
• 536-74-3 phenylacetylene 
• 1011-84-3 4-nitrobenzohydroximoyl chloride 
• 881214-06-8 1,1-dimethylethyl (4-((1Z)-1-hydroxy-3-oxo-3-phenyl-3-phenylprop-1-en-1-yl)-phenyl)-carbamate 
• 100-52-7 benzaldehyde 
• 2403-30-7 4'-aminochalcone 
• 42558-04-3 4-(5-Phenyl-4,5-dihydro-1H-pyrazol-3-yl)-phenylamine 

Relevant articles and documents

Discovery of 5-aryl-3-thiophen-2-yl-1H-pyrazoles as a new class of Hsp90 inhibitors in hepatocellular carcinoma

Although hepatocellular carcinoma (HCC)-related mortality has increased over the past decades, treatment options are still very limited, underlining the need for developing new therapeutic strategies. The molecular chaperone heat shock protein 90 (Hsp90)

PYRAZOLE KINASE MODULATORS AND METHODS OF USE

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferationm, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/0r modulate kinases. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.