82964-91-8

Basic information

• Product Name: 4-METHYLSULFONYLBENZENESULFONYL CHLORIDE
• Synonyms: 4-METHYLSULFONYLBENZENESULFONYL CHLORIDE;4-METHYLSULPHONYLBENZENESULPHONYL CHLORIDE;4-METHYLSULPHONYLBENZENESULPHONYL CHLORIDE 95%;4-Methylsulfonylbenzenesulphonyl chloride;4-(Methylsulfonyl)benzenesulfonyl chloride,95%;4-(Chlorosulphonyl)phenyl methyl sulphone;4-(Methylsulfonyl)benzene-1-sulfonyl chloride;4-(Methylsulfonyl)benzenesulfonyl chloride 97%
• CAS NO: 82964-91-8
• Molecular Formula: C₇H₇ClO₄S₂
• Molecular Weight: 254.71
• Product Categories: Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 82964-91-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 165-169 °C(lit.)
• Boiling Point: 158-163°C
• Flash Point: 208.8 °C
• Appearance: Yellow to salmon-pink/Crystalline Powder
• Density: 1.4936 (estimate)
• Vapor Pressure: 6.26E-07mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-METHYLSULFONYLBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYLSULFONYLBENZENESULFONYL CHLORIDE(82964-91-8)
• EPA Substance Registry System: 4-METHYLSULFONYLBENZENESULFONYL CHLORIDE(82964-91-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 22-26-36/37/39-45-24/25
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 82964-91-8(Hazardous Substances Data)

Usage

Chemical Properties

yellow to salmon-pink crystalline powder

Uses

4-(Methylsulfonyl)benzenesulfonyl chloride may be used in the preparation of 5′-deoxy-5′-[4-(methylsulfonyl)benzenesulfonamido]thymidine.

InChI:InChI=1/C7H7ClO4S2/c1-13(9,10)6-2-4-7(5-3-6)14(8,11)12/h2-5H,1H3

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 15898-43-8 sodium 4-acetamidobenzenesulfinate 
• 22821-80-3 N-(4-methanesulfonylphenyl)acetamide 
• 5470-49-5 4-methanesulfonylphenylamine 
• 1129-25-5 4-(methylsulfanyl)benzenesulfonyl chloride 

Downstream Products

• 1015168-69-0 N'-(4-(methylsulfonyl)phenylsulfonyl)-N,4-diethyl-4,5-dihydro-1H-pyrazole-1-carboxamidine 
• 1415586-36-5 C₁₉H₂₃NO₆S₂ 
• 1415586-37-6 C₂₀H₂₅NO₆S₂ 
• 1415586-35-4 C₂₀H₂₅NO₅S₂ 
• 1415586-38-7 C₂₁H₂₇NO₇S₃ 
• 1415586-40-1 C₂₁H₂₅NO₇S₃ 
• 1415586-39-8 C₂₂H₂₉NO₇S₃ 
• 1415586-41-2 C₂₂H₂₇NO₇S₃ 
• 1415586-42-3 C₂₂H₃₁NO₇S₂ 
• 1415586-43-4 C₁₈H₂₁NO₆S₂ 
• 1415586-34-3 C₁₆H₁₉NO₅S₂ 
• 1415586-48-9 C₁₈H₂₃NO₆S₂ 
• 1423077-41-1 N-(3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl)-4-(methylsulfonyl)benzenesulfonamide 
• 1315565-48-0 2-(4-methanesulfonyl-benzenesulfonyl)-2-methyl-propionic acid 

Relevant articles and documents

INTEGRIN EXPRESSION INHIBITORS

The present invention provides an integrin expression inhibitor, and an agent for treating arterial sclerosis, psoriasis, cancer, retinal angiogenesis, diabetic retinopathy or inflammatory diseases, an anticoagulant, or a cancer metastasis suppressor on the basis of an integrin inhibitory action. Namely, it provides an integrin expression inhibitor comprising, as an active ingredient, a sulfonamide compound represented by the following formula (I), a pharmacologically acceptable salt thereof or a hydrate of them. In the formula, B means a C6-C10 aryl ring or 6- to 10-membered heteroaryl ring which may have a substituent and in which a part of the ring may be saturated; K means a single bond, -CH=CH- or - (CR4bR5b)mb- (wherein R4b and R5b are the same as or different from each other and each means hydrogen atom or a C1-C4 alkyl group; and mb means an integer of 1 or 2); R1 means hydrogen atom or a C1-C6 alkyl group; Z means a single bond or -CO-NH-; and R means a C6-C10 aryl ring or 6- to 10-membered heteroaryl ring which may have a substituent and in which a part of the ring may be saturated, respectively.

Bispiperidines as antithrombotic agents

Novel compounds which are inhibitors of the binding of fibrinogen to the Gp IIb/IIIa platelet receptors, and which can be used therepeutically as antithrombotic agents

Sulfonyl esters 7. The second and third sequences in the Trithioorthoformate Reaction

A previous report has established the intermediacy of a sulfide-sulfonate ester in the one-pot conversion of an aryl mercaptan and a sulfonate ester into the corresponding trithioorthoformate. This report describes evidence for the sequential intermediacy of a bissulfide-sulfonate ester and a dithiosulfene in the conversion of the sulfide-sulfonate ester into the trithioorthoformate. A new sulfonate ester is shown to give the highest yield of trithioorthoformate.