83-89-6

Basic information

• Product Name: QUINACRINE DIHYDROCHLORIDE DIHYDRATE
• Synonyms: 2-methoxy-6-chloro-9-diethylaminopentylaminoacridine;3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine;6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxy-acridin;6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine;6-chloro-9-((4-(dimethylamino)-1-methylbutyl)amino)-2-methoxyacridine;acrichine;acrinamine;acriquine
• CAS NO: 83-89-6
• Molecular Formula: C₂₃H₃₀ClN₃O
• Molecular Weight: 508.91
• EINECS: 201-508-7
• Product Categories: ATABRINE
• Mol File: 83-89-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 247-250 °C
• Boiling Point: 557.1 °C at 760 mmHg
• Flash Point: 290.7 °C
• Appearance: /
• Density: 1.0989 (rough estimate)
• Refractive Index: 1.5790 (estimate)
• CAS DataBase Reference: QUINACRINE DIHYDROCHLORIDE DIHYDRATE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINACRINE DIHYDROCHLORIDE DIHYDRATE(83-89-6)
• EPA Substance Registry System: QUINACRINE DIHYDROCHLORIDE DIHYDRATE(83-89-6)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-22
• Safety Statements: 37/39-26
• Hazardous Substances Data: 83-89-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 83-89-6 differently. You can refer to the following data:
1. anthelmintic, antimalarial, intercalating agent
2. Quinacrine is an acridine that was used extensively from the mid-1920s to the end of World War II. It acts much like chloroquine and is reasonably effective. Because it causes the skin to turn yellow and, in high doses, causes yellow vision, the drug is no longer in use as an antimalarial.

Definition

ChEBI: A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.

Safety Profile

Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. Mutation data reported. Experimental reproductive effects. Has been implicated in aplas tic anemia. When heated to decomposition, it emits very toxic fumes of Cland NOx.

InChI:InChI=1/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)

Upstream product

• 140-80-7 5-diethylamino-2-pentylamine 
• 4822-25-7 N-(6-chloro-2-methoxy-acridin-9-yl)-acetamide 
• 57623-77-5 2-p-anisidino-4-chloro-benzoyl chloride 
• 83-89-6 quinacrine 
• 7478-26-4 6-chloro-2-methoxy-9-phenoxyacridine 
• 86-38-4 6,9-dichloro-2-methoxyacridine 
• 124-30-1 1-aminooctadecane 
• 108-95-2 phenol 
• 210584-71-7 6-chloro-2,9-dimethoxyacridine 
• 3548-09-2 6-chloro-2-methoxyacridin-9-amine 
• 2411-88-3 6-chloro-9-mercapto-2-methoxy-acridine 
• 4822-23-5 (6-chloro-2-methoxy-acridin-9-yl)-methyl-amine 

Downstream Products

• 83-89-6 (+)-N⁴,N⁴-diethyl-N¹-(6-chloro-2-methoxy-acridin-9-yl)-1-methyl-butanediyldiamine 
• 83-89-6 (-)-N⁴,N⁴-diethyl-N¹-(6-chloro-2-methoxy-acridin-9-yl)-1-methyl-butanediyldiamine 

Relevant articles and documents

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