84547-84-2

Basic information

• Product Name: 4-bromo-1-methylpyrazole-3-carboxy acid
• Synonyms: 4-bromo-1-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE);4-Bromo-2-methylpyrazole-3-carboxylic acid;1-Methyl-4-bromopyrazole-5-carboxylic acid;4-bromo-1-methylpyrazole-3-carboxy acid
• CAS NO: 84547-84-2
• Molecular Formula: C₅H₅BrN₂O₂
• Molecular Weight: 205.01
• Mol File: 84547-84-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 235-236 °C
• Boiling Point: 347.4 °C at 760 mmHg
• Flash Point: 163.9 °C
• Appearance: /
• Density: 1.93 g/cm³
• Vapor Pressure: 2.03E-05mmHg at 25°C
• Refractive Index: 1.658
• Storage Temp.: 2-8°C
• PKA: 1.75±0.37(Predicted)
• CAS DataBase Reference: 4-bromo-1-methylpyrazole-3-carboxy acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-1-methylpyrazole-3-carboxy acid(84547-84-2)
• EPA Substance Registry System: 4-bromo-1-methylpyrazole-3-carboxy acid(84547-84-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 84547-84-2(Hazardous Substances Data)

Usage

General Description

4-bromo-1-methylpyrazole-3-carboxylic acid is a chemical compound with the molecular formula C6H6BrN2O2. It is a derivative of pyrazole, and the presence of the bromine group suggests that it is likely to be used in organic synthesis or as a building block for the creation of more complex molecules. The methyl and carboxylic acid groups indicate that it may have properties relevant to medicinal or pharmacological applications, as these functional groups are often found in drug molecules. Overall, 4-bromo-1-methylpyrazole-3-carboxylic acid is a versatile compound with potential uses in various fields of chemistry and biology.

InChI:InChI=1/C5H5BrN2O2/c1-8-4(5(9)10)3(6)2-7-8/h2H,1H3,(H,9,10)

Upstream product

• 15803-02-8 4-bromo-1-methyl-1H-pyrazole 
• 591-51-5 phenyllithium 
• 13808-64-5 4-bromo-3-methyl-1H-pyrazole 
• 124-38-9 carbon dioxide 
• 694-31-5 1,5-dimethyl-1H-pyrazole 
• 16034-46-1 1-methyl-1H-pyrazole-5-carboxylic acid 
• 5775-86-0 4-bromo-1,5-dimethyl-1H-pyrazole 

Relevant articles and documents

Compound for treatment on hepatitis B and use thereof

The invention relates to a compound for treatment on hepatitis B and a use thereof. Specifically, the invention discloses a compound as a HBV replication inhibitor having the structure shown in the formula (A), or its stereoisomer, tautomer, pharmaceutically acceptable salt, hydrate or solvate. The groups are detailed in the specification. The invention also relates a pharmaceutical composition containing the compound and a use thereof in treatment on hepatitis B.

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.