845965-30-2

Basic information

• Product Name: (6R,7aS)-6-Hydroxy-1,1-diphenyl-tetrahydro-pyrrolo[1,2-c]oxazol-3-one
• Synonyms: (6R,7aS)-6-Hydroxy-1,1-diphenyl-tetrahydro-pyrrolo[1,2-c]oxazol-3-one
• CAS NO: 845965-30-2
• Molecular Weight: 295.338
• Mol File: 845965-30-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (6R,7aS)-6-Hydroxy-1,1-diphenyl-tetrahydro-pyrrolo[1,2-c]oxazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (6R,7aS)-6-Hydroxy-1,1-diphenyl-tetrahydro-pyrrolo[1,2-c]oxazol-3-one(845965-30-2)
• EPA Substance Registry System: (6R,7aS)-6-Hydroxy-1,1-diphenyl-tetrahydro-pyrrolo[1,2-c]oxazol-3-one(845965-30-2)

Safety Data

• Hazardous Substances Data: 845965-30-2(Hazardous Substances Data)

Upstream product

• 845965-29-9 (6R,7aS)-1,1-Diphenyl-6-(tetrahydro-pyran-2-yloxy)-tetrahydro-pyrrolo[1,2-c]oxazol-3-one 
• 172947-80-7 (2S,4R)-1-ethyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 
• 845965-33-5 1-ethyl 2-methyl (2S,4R)-4-(tetrahydro-2H-pyran-2-yloxy)pyrrolidine-1,2-dicarboxylate 
• 100-58-3 phenylmagnesium bromide 
• 83487-17-6 (2S,4R)-(-)-N-methyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 
• 344791-02-2 (2S,4R)-4-hydroxy-2-(1-hydroxy-1,1-diphenylmethyl)pyrroline-1-carboxylic acid tert-butyl ester 

Downstream Products

• 176747-44-7 (2S,4R)-4-hydroxy-α,α-diphenyl-2-pyrrolidinemethanol 

Relevant articles and documents

Polymer-Supported Chiral Cis-Disubstituted Pyrrolidine Catalysts and Their Application to Batch and Continuous-Flow Systems

Polymer-supported cis-pyrrolidine catalysts were developed that allowed for high enantioselectivity and diastereoselectivity compared with those obtained from common trans-pyrrolidine catalysts. Not only configurational but also polymeric effects contribute to the high diastereoselectivity and enantioselectivity. Polymer catalysts were also successfully applied in a continuous-flow process. Acceleration of the reaction rate, an increase in diastereoselectivity, and an improvement in durability were observed in continuous-flow operation compared with the batch system.

NOVEL NI COMPLEX AND ITS DERIVATIVES, PRODUCING METHOD, AND THE USE THEREOF AS AN ANTIOXIDANT

The present invention relates to a novel nickel complex and its derivatives, which mimic the active site of Ni-containing superoxide dismutase (NiSOD). The five-coordinate Ni(II) and Ni(III) complexes or their derivatives, and six-coordinate derivatives have the following structures of formula (I) and (II): The nickel complexes and their derivatives of the invention act as anti-oxidants or free radical scavengers. The invented nickel complexes can be used in the preparation of medicines, health foods or cosmetics for human, animals and plants, or can be used in environmental or soil protection.