847727-77-9

Basic information

• Product Name: 4-[(1S)-1-({[5-chloro-2-(4-fluorophenoxy)pyridine-3-yl]carbonyl}amino)ethyl]benzoic acid
• Synonyms: 4-[(1S)-1-({[5-chloro-2-(4-fluorophenoxy)pyridine-3-yl]carbonyl}amino)ethyl]benzoic acid
• CAS NO: 847727-77-9
• Molecular Weight: 414.82
• Mol File: 847727-77-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-[(1S)-1-({[5-chloro-2-(4-fluorophenoxy)pyridine-3-yl]carbonyl}amino)ethyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1S)-1-({[5-chloro-2-(4-fluorophenoxy)pyridine-3-yl]carbonyl}amino)ethyl]benzoic acid(847727-77-9)
• EPA Substance Registry System: 4-[(1S)-1-({[5-chloro-2-(4-fluorophenoxy)pyridine-3-yl]carbonyl}amino)ethyl]benzoic acid(847727-77-9)

Safety Data

• Hazardous Substances Data: 847727-77-9(Hazardous Substances Data)

Upstream product

• 59782-85-3 2,5-dichloronicotinic acid 
• 847729-02-6 tert-butyl 4-[(1S)-1-aminoethyl]benzoate 
• 847729-04-8 tert-butyl 4-[(1S)-1-[(2,5-dichloropyridin-3-yl)formamido]ethyl]benzoate 

Relevant articles and documents

Discovery of AAT-008, a novel, potent, and selective prostaglandin EP4 receptor antagonist

Starting from acylsufonamide HTS hit 2, a novel series of para-N-acylaminomethylbenzoic acids was identified and developed as selective prostaglandin EP4 receptor antagonists. Structural modifications on lead compound 4a were explored with the aim of impr

COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS

The instant invention relates to a combination of an EP4-receptor antagonist and an alpha-2-delta ligand, and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof and their use in the treatment of pain, particularly inflammatory,