847729-04-8Relevant articles and documents
Discovery of AAT-008, a novel, potent, and selective prostaglandin EP4 receptor antagonist
Okumura, Yoshiyuki,Yamagishi, Tatsuya,Nukui, Seiji,Nakao, Kazunari
supporting information, p. 1186 - 1192 (2017/06/21)
Starting from acylsufonamide HTS hit 2, a novel series of para-N-acylaminomethylbenzoic acids was identified and developed as selective prostaglandin EP4 receptor antagonists. Structural modifications on lead compound 4a were explored with the aim of impr
COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS
-
, (2008/06/13)
The instant invention relates to a combination of an EP4-receptor antagonist and an alpha-2-delta ligand, and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof and their use in the treatment of pain, particularly inflammatory,