851460-92-9

Basic information

• Product Name: N-allyl-2-chlorobenzenesulfonamide
• Synonyms: N-allyl-2-chlorobenzenesulfonamide
• CAS NO: 851460-92-9
• Molecular Weight: 231.703
• Mol File: 851460-92-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-allyl-2-chlorobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-allyl-2-chlorobenzenesulfonamide(851460-92-9)
• EPA Substance Registry System: N-allyl-2-chlorobenzenesulfonamide(851460-92-9)

Safety Data

• Hazardous Substances Data: 851460-92-9(Hazardous Substances Data)

Upstream product

• 107-11-9 1-amino-2-propene 
• 2905-23-9 2-chlorophenylsulfonyl chloride 
• 6961-82-6 2-chlorobenzenesulfonamide 
• 106-95-6 allyl bromide 

Downstream Products

• 851460-99-6 dithiocarbonic acid S-[2-(2-chlorobenzenesulfonylamino)-1-(2-oxotetrahydrofuran-3-yl-methyl)ethyl] ester O-ethyl ester 
• 851461-07-9 dithiocarbonic acid S-[2-[acetyl(2-chlorobenzenesulfonyl)amino]-1-(2-oxotetrahydrofuran-3-yl-methyl)ethyl] ester O-ethyl ester 
• 1208004-12-9 N-(2-fluoro-propyl)-2-chloro-benzenesulfonamide 
• 1421639-26-0 1-(2-chlorophenylsulfonyl)-3-methyl-2,5-dihydro-1H-pyrrole 
• 1421639-23-7 N-allyl-2-chloro-N-(2-methylallyl)benzenesulfonamide 

Relevant articles and documents

Tert-Butyl Nitrite: Organic Redox Cocatalyst for Aerobic Aldehyde-Selective Wacker-Tsuji Oxidation

An aldehyde-selective aerobic Wacker-Tsuji oxidation is developed. Using tert-butyl nitrite as a simple organic redox cocatalyst instead of copper or silver salts, a variety of aldehydes were achieved as major products in up to 30/1 regioselectivity as well as good to high yields at room temperature.

Synthesis of substituted 3-arylpiperidines and 3-arylpyrrolidines by radical 1,4 and 1,2-aryl migrations

A route to 3-arylpiperidines and 3-arylpyrrolidines involving radical 1,4- and 1,2-aryl migrations has been explored. For the piperidines, the first route requires a xanthate addition to an N-allylarylsulfonamide, followed by acetylation and treatment with lauroyl peroxide to give the corresponding 1,4-aryl transfer product. This compound can be converted into the desired piperidine derivative following acidic hydrolysis. For the second approach to piperidines, addition of an α-keto xanthate to olefins of type 14 causes 1,2-aryl migration leading to an α,β-unsaturated ester, which can be converted into a piperidine by the action of ammonia or a primary amine and sodium cyanoborohydride. Substituted 3-arylpyrrolidines can be obtained by simply starting with an α-amido substituted xanthate.