85443-46-5Relevant articles and documents
Asymmetric SN 1 α-Alkylation of cyclic ketones catalyzed by functionalized chiral ionic liquid (FCIL) organocatalysts
Zhang, Long,Cui, Lingyun,Li, Xin,Li, Jiuyuan,Luo, Sanzhong,Cheng, Jin-Pei
supporting information; scheme or table, p. 2045 - 2049 (2010/06/15)
Ionic liquid works better: The first intermolecular asymmetric α-alkylation of cyclic ketones was realized by using functionalized chiral ionic liquids as catalysts. The reaction proceeded with good to excellent yields and high ee. Highly stereoselective desymmetrization of 4-substituted cyclohexanones with >99:1 d.r. and up to 87 % ee were achieved by using this protocol. (Chemical Equation Representation).