857589-14-1Relevant articles and documents
Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization
Yang, Chao,Lin, Kai,Huang, Lan,Pan, Wei-Dong,Liu, Sheng
supporting information, p. 2490 - 2494 (2016/12/07)
A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3-4 steps based on commercially available starting materials.
Palladium- and copper-catalyzed site selective monoamination of dibromobenzoic acid
Houpis, Ioannis N.,Weerts, Koen,Nettekoven, Ulrike,Canters, Martine,Tan, Hongyu,Liu, Renmao,Wang, Youchu
supporting information; experimental part, p. 538 - 544 (2011/04/23)
The carboxylate anion has been used as a directing group in the aromatic amination of electronically equivalent aryl bromides to afford selective ortho-substituted derivatives (> 99:1 selectivity; 60-80% yield) in the case of copper(I) catalysis. The solvent, base and equivalents of base were important factors in the success of this reaction. Complementary selectivity was achieved with palladium catalysis where the para-substituted derivatives were produced selectively (> 99% selectivity, 70-80% yield).
