858116-59-3 Usage
Molecular structure
The compound consists of a pyrrolopyridine ring system with an amine group attached to the nitrogen atom at position 3. The amine nitrogen is further substituted with an N,N-dimethyl group and a tris(1-methylethyl)silyl group.
Biological activity
Pyrrolopyridine derivatives are known for their potential therapeutic properties and biological activity.
Pharmacological properties
The addition of the N,N-dimethyl-1-[tris(1-methylethyl)silyl] group may enhance the compound's pharmacological properties.
Solubility and stability
The tris(1-methylethyl)silyl group may improve the compound's solubility and stability in biological systems.
Potential applications
The compound has potential applications in medicinal chemistry and drug development, and could be of interest for researchers and pharmaceutical companies working on the development of new drug candidates targeting various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 858116-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,1,1 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 858116-59:
(8*8)+(7*5)+(6*8)+(5*1)+(4*1)+(3*6)+(2*5)+(1*9)=193
193 % 10 = 3
So 858116-59-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H33N3Si/c1-14(2)23(15(3)4,16(5)6)22-13-17(12-21(7)8)18-10-9-11-20-19(18)22/h9-11,13-16H,12H2,1-8H3
858116-59-3Relevant articles and documents
Compounds and methods for development of Ret modulators
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Page/Page column 66, (2008/06/13)
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
