858116-79-7 Usage
Structure
Substituted pyrrolopyridine derivative with a bromine atom and N,N-dimethyl-1-[tris(1-methylethyl)silyl] substituents
Usage
Building block for the preparation of biologically active molecules in organic synthesis and pharmaceutical research
Application
Development of new drugs and agrochemicals due to unique structural properties
Check Digit Verification of cas no
The CAS Registry Mumber 858116-79-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,8,1,1 and 6 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 858116-79:
(8*8)+(7*5)+(6*8)+(5*1)+(4*1)+(3*6)+(2*7)+(1*9)=197
197 % 10 = 7
So 858116-79-7 is a valid CAS Registry Number.
InChI:InChI=1/C19H32BrN3Si/c1-13(2)24(14(3)4,15(5)6)23-12-16(11-22(7)8)18-17(20)9-10-21-19(18)23/h9-10,12-15H,11H2,1-8H3
858116-79-7Relevant articles and documents
Compounds and methods for development of Ret modulators
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Page/Page column 66, (2008/06/13)
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and strucural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
