Cas 860616-71-3,6-(4-benzyloxy-phenyl)-spiro[2.5]octane

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Check Digit Verification of cas no

The CAS Registry Mumber 860616-71-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,6,1 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 860616-71:
(8*8)+(7*6)+(6*0)+(5*6)+(4*1)+(3*6)+(2*7)+(1*1)=173
173 % 10 = 3
So 860616-71-3 is a valid CAS Registry Number.

860616-71-3Upstream product

82240-03-7 4-(4-(benzyloxy)phenyl)cyclohexan-1-one

860616-71-3Downstream Products

860616-51-9 6-[4-(3-bromo-propoxy)-3-chloro-phenyl]-spiro[2.5]octane

860616-71-3Relevant articles and documents

(2R)-2-Methylchromane-2-carboxylic acids: Discovery of selective PPARα agonists as hypolipidemic agents

Koyama, Hiroo,Boueres, Julia K.,Miller, Daniel J.,Berger, Joel P.,MacNaul, Karen L.,Wang, Pei-Ran,Ippolito, Marc C.,Wright, Samuel D.,Agrawal, Arun K.,Moller, David E.,Sahoo, Soumya P.

, p. 3347 - 3351 (2005)

A SAR study was conducted on chromane-2-carboxylic acid toward selective PPARα agonisim. As a result, highly potent, and selective PPARα agonists were discovered. The optimized compound 43 exhibited robust lowering of total cholesterol levels in hamster and dog animal models.

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860616-71-3